Results 81 to 90 of about 3,757,828 (333)

Clinical Diagnosis of Placenta Accreta and Clinicopathological Outcomes [PDF]

open access: yes, 2019
Objective To investigate the association between the intraoperative diagnosis of placenta accreta at the time of cesarean hysterectomy and pathological diagnosis.
Cahill, Alison G.   +5 more
core   +1 more source

Role of ROS and RNS Sources in Physiological and Pathological Conditions

open access: yesOxidative Medicine and Cellular Longevity, 2016
There is significant evidence that, in living systems, free radicals and other reactive oxygen and nitrogen species play a double role, because they can cause oxidative damage and tissue dysfunction and serve as molecular signals activating stress ...
S. Di Meo   +3 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Valor del diagnóstico de la tuberculosis pulmonar por autopsia en Cuba Importance of the pulmonary tuberculosis diagnosis by autopsy in Cuba

open access: yesRevista Habanera de Ciencias Médicas, 2012
El diagnóstico de la tuberculosis pulmonar por autopsia mide la calidad de la atención médica y el comportamiento de la enfermedad. Objetivo: Determinar los fallecidos que murieron con y por Tuberculosis pulmonar y la concordancia entre los diagnósticos ...
Ana Ivonne Martínez Portuondo   +2 more
doaj  

Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]

open access: yes, 2010
An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier   +49 more
core   +2 more sources

Osteoarthritis: toward a comprehensive understanding of pathological mechanism

open access: yesBone Research, 2017
Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA includes joint injury, obesity, aging, and heredity.
Di Chen   +6 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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