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Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

Allergy, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...
Bernardo Sousa‐Pinto +252 more
wiley +1 more source

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen +10 more
wiley +1 more source

Predictors of depressive symptoms and depression in women with previous pregnancy loss

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Depressive symptoms are common in females after pregnancy loss. However, research on risk factors for developing a clinical depressive episode remains limited and with inconsistent findings. This study examined the association of demographic variables (like age), pregnancy‐related factors (like number of miscarriages or stillbirths),
Sarah M. Quaatz +6 more
wiley +1 more source

Hydraulic and malleable female‐to‐male penile implants after phalloplasty in transgender individuals: a retrospective cohort analysis

BJU International, EarlyView.
Objectives To provide a comprehensive summary of the surgical outcomes of Zephyr Surgical Implants (ZSI; Geneva, Switzerland) hydraulic and malleable female‐to‐male (FTM) penile implants (PIs) in transgender patients. Patients and Methods All transgender patients who underwent hydraulic (ZSI FTM 475) and malleable (ZSI FTM 100) erectile device ...
Maya Levy +6 more
wiley +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source

Accountability and Hyperaccountability in Child Protection Scandals

Child &Family Social Work, EarlyView.
ABSTRACT The number of child abuse–related deaths has decreased significantly in the United Kingdom over the past 50 years, but there remains public and political concern about the actual and perceived risk of child deaths, with resultant processes enacted to supervise child protection practice.
Robin Sen, John Devaney
wiley +1 more source

Personality disorders and pathological gambling. [PDF]

Curr Opin Psychiatry, 2017
Vaddiparti K, Cottler LB.
europepmc +1 more source

Intermediate Effects Between Experiences of Violence at Home, School, Street, TV and Child‐to‐Parent Violence

Child &Family Social Work, EarlyView.
ABSTRACT Exposure to violence is an adverse experience related to child‐to‐parent violence. The objectives were to examine differences in child‐to‐parent violence according to the sex and age of the children and to analyse the mediating role of reactive and instrumental reasons between exposure to direct and indirect violence across different contexts ...
Luis Burgos‐Benavides +3 more
wiley +1 more source

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