Results 111 to 120 of about 1,076,017 (253)

Morphologic Features of Myopic Choroidal Neovascularization in Pathologic Myopia on Swept-Source Optical Coherence Tomography [PDF]

, 2020
Jiamin Xie, Qiuying Chen, Jiayi Yu, Hao Zhou, Jiangnan He, Weijun Wang, Ying Fan, Xun Xu   +7 more
openalex   +1 more source

Vascular flow density in pathological myopia: an optical coherence tomography angiography study

BMJ Open, 2017
Objectives To investigate vascular flow density in pathological myopia with optical coherence tomography (OCT) angiography. Design A prospective comparative study was conducted from December 2015 to March 2016.
Jing Mo, An-li Duan, S. Chan, Xuefei Wang, W. Wei   +4 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Real-World Anti-Vascular Endothelial Growth Factor Therapy Outcomes in Myopic Choroidal Neovascularization

Clinical Ophthalmology, 2021
Devangna Bhatia, Alexander Mehta, Joanna DaCosta, Oonagh Crothers, James Stephen Talks Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, UKCorrespondence: Devangna BhatiaNewcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon ...
Bhatia D, Mehta A, DaCosta J, Crothers O, Talks JS   +4 more
doaj  

Altered Functional Specialization and Interhemispheric Coordination in Rhegmatogenous Retinal Detachment: Associations With Gene Expression, Neurotransmitter Receptor Distribution, and SVM–SHAP Classification

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Autonomy Index (AI) and Connective Flexibility of Homotopic voxels (CFH) were derived from resting‐state fMRI data following standard preprocessing. These functional metrics were computed based on the AAL90 atlas to characterize intrinsic activity and interhemispheric coordination patterns in RRD patients.
Yu Ji, Yuan‐Yuan Wang, Xiao‐Rong Wu
wiley   +1 more source

Foundation models in ophthalmology: a preliminary study on AI-assisted diagnosis of myopic maculopathy and posterior staphyloma using ultra-widefield fundus images

BMJ Open Ophthalmology
Objectives This study aims to detect characteristic fundus changes in pathological myopia using deep learning (DL)-based analysis of ultra-widefield (UWF) fundus imaging.Methods Following the exclusion of low-quality images, this cross-sectional study ...
Tao Yu, Hao Zhou, Haidong Zou, Senlin Lin, Yingyan Ma, Xian Xu, Yuzhu Zhang, Juzhao Zhang, Mengjia Zhang, Wenwen Xue   +9 more
doaj   +1 more source

Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults

Journal of Ophthalmology, 2017
Purpose. To quantify macular vascular density using optical coherence tomography angiography (OCTA) and to investigate its relationship with retinal thickness in myopic eyes of young adults. Methods. In this cross-sectional study, 268 myopic eyes without
Shiqi Yang, Minwen Zhou, Bing Lu, Pengfei Zhang, Jingke Zhao, Mei Kang, Ruoshi Wang, Fenghua Wang, Xiaodong Sun   +8 more
doaj   +1 more source

Scleral rupture during intraoperative silicone oil injection in pars plana vitrectomy

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report a single case history of scleral rupture (SR) during silicone oil injection in a pars plana vitrectomy. Observations: A 60-year-old woman with a history of pathological myopia presented with acute vision loss in her right eye.
Ana Laura Domínguez Yates, Jimena Rojas, Mario Joaquín Saravia   +2 more
doaj   +1 more source

Perspective of the Pharmaceuticals and Medical Devices Agency on Drug Development for Childhood Myopia

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 26-29, January 2026.
Pathologic myopia represents a global public health concern, with increasing prevalence and vision loss risk. Myopia typically develops in childhood and progresses more rapidly with earlier onset. Clinical trials exploring treatments for decelerating myopia progression are underway.
Mitsuru Arima, Motomasa Atsumi, Kumiko Takeuchi, Takumi Aoki, Emi Inagaki, Yosuke Kobayashi, Takuya Kageyama, Kazuki Izumi, Atsushi Yoshimura, Wataru Asakura   +9 more
wiley   +1 more source