Results 111 to 120 of about 452,384 (232)

Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults

Journal of Ophthalmology, 2017
Purpose. To quantify macular vascular density using optical coherence tomography angiography (OCTA) and to investigate its relationship with retinal thickness in myopic eyes of young adults. Methods. In this cross-sectional study, 268 myopic eyes without
Shiqi Yang, Minwen Zhou, Bing Lu, Pengfei Zhang, Jingke Zhao, Mei Kang, Ruoshi Wang, Fenghua Wang, Xiaodong Sun   +8 more
doaj   +1 more source

Algorithmic Monoculture and Its Critics

Philosophical Perspectives, EarlyView.
ABSTRACT Algorithmic decision‐making is replacing idiosyncratic human judgment in domains such as hiring, lending, and criminal justice. This shift promises increased consistency, but many scholars worry that it can go too far. They warn of the dangers of algorithmic monoculture, in which all decisions across a domain are made using a single algorithm.
Brian Hedden, Manish Raghavan
wiley   +1 more source

Foundation models in ophthalmology: a preliminary study on AI-assisted diagnosis of myopic maculopathy and posterior staphyloma using ultra-widefield fundus images

BMJ Open Ophthalmology
Objectives This study aims to detect characteristic fundus changes in pathological myopia using deep learning (DL)-based analysis of ultra-widefield (UWF) fundus imaging.Methods Following the exclusion of low-quality images, this cross-sectional study ...
Tao Yu, Hao Zhou, Haidong Zou, Senlin Lin, Yingyan Ma, Xian Xu, Yuzhu Zhang, Juzhao Zhang, Mengjia Zhang, Wenwen Xue   +9 more
doaj   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Real-World Anti-Vascular Endothelial Growth Factor Therapy Outcomes in Myopic Choroidal Neovascularization

Clinical Ophthalmology, 2021
Devangna Bhatia, Alexander Mehta, Joanna DaCosta, Oonagh Crothers, James Stephen Talks Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, UKCorrespondence: Devangna BhatiaNewcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon ...
Bhatia D, Mehta A, DaCosta J, Crothers O, Talks JS   +4 more
doaj  

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, Volume 159, Issue 7, Page 1707-1714, 1 October 2026.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Comprehensive analysis of posterior segment characteristics in high myopic Turkish patients

BMC Ophthalmology
Background We aimed to investigate the structural characteristics of high myopia (HM) in a Turkish cohort using spectral domain optical coherence tomography (OCT) and evaluate the relationship between axial length (AL) and various retinal, choroidal, and
Mustafa Kayabaşı, Ali Osman Saatci, Neslihan Demirel, Ziya Ayhan, Mahmut Kaya, Zeynep Özbek, Taylan Öztürk   +6 more
doaj   +1 more source

Epidemiology of pathologic myopia in UK adults with high myopia

British Journal of Ophthalmology
Aims To conduct the first cross-sectional epidemiological investigation of pathologic myopia (PM) in UK adults with high myopia. Methods Fundus photographs of 3024 highly myopic eyes (spherical equivalent refraction (SER) ≤−5.00D) from
Fabian Yii, Niall Strang, Miguel O. Bernabeu, Baljean Dhillon, Tom MacGillivray, Ian J.C. MacCormick   +5 more
openaire   +5 more sources

Understanding higher‐order aberrations in keratoconus

Optometry and Vision Science, Volume 103, Issue 10, October 2026.
ABSTRACT Keratoconus is characterized by progressive thinning and increasing irregularity of the cornea, leading to substantial degradation in optical quality through the induction of both lower‐ and higher‐order aberrations (HOAs). In addition to inducing myopic and astigmatic refractive error, asymmetric corneal steepening generates complex optical ...
Gavin Swartz, Khyber Alam, Alex Gentle, Laura E. Downie   +3 more
wiley   +1 more source