Results 41 to 50 of about 452,384 (232)

Pathologic Myopia

Asia-Pacific Journal of Ophthalmology, 2016
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma).
openaire   +4 more sources

Corneal morphometric and biomechanical properties in patients with pathological and uncomplicated high myopia

Офтальмохирургия
Relevance. Pathological myopia leads to development of myopic maculopathy, which results in impaired visual functions. Formation of retinal pathological changes in the posterior pole of the eye in myopia is based on axial elongation of the eye and the ...
L.V. Bushnina, O.V. Kolenko, N.V. Pomytkina, E.L. Sorokin, Ya.E. Pashentsev   +4 more
doaj   +1 more source

Peripapillary Detachment in Pathologic Myopia [PDF]

Archives of Ophthalmology, 2003
To describe peripapillary detachment in pathologic myopia (PDPM), a newly recognized fundus lesion.Retrospective medical record review.We evaluated a series of myopic eyes that had a yellow-orange elevation of the retina and retinal pigment epithelium at the inferior border of the myopic conus.Twenty eyes of 15 patients were identified during a 17-year
K Bailey, Freund, Antonio P, Ciardella, Lawrence A, Yannuzzi, Alfredo, Pece, Mauro, Goldbaum, Gregg T, Kokame, Dennis, Orlock   +6 more
openaire   +2 more sources

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Clinical study of pathological myopia [PDF]

, 2013
HISTORY: Myopia is well known even since ancient period. The word Myopia is a Greek word, which means “to shut” or “to close the eye”. The original meaning of the word Myopia was meant to describe the condition where the patient attempts to see ...
Kumaravel, T
core  

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

Phacoemulsification with Negative Power IOL Implantation in Pathological Myopia: A Life-changing Procedure

Delhi Journal of Ophthalmology
Pathological myopia refers to a spherical equivalent of −8.00 D or more or axial length of 32.5 mm or more. Pathological myopia can lead to complications of the posterior segment such as retinal detachment and staphyloma in long term.
Dharti Punjabi, Devika S. Joshi, Vishranti Khandelwal   +2 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Advances of optical coherence tomography in myopia and pathologic myopia [PDF]

Eye, 2016
The natural course of high-axial myopia is variable and the development of pathologic myopia is not fully understood. Advancements in optical coherence tomography (OCT) technology have revealed peculiar intraocular structures in highly myopic eyes and unprecedented pathologies that cause visual impairment. New OCT findings include posterior precortical
D S C, Ng, C Y L, Cheung, F O, Luk, S, Mohamed, M E, Brelen, J C S, Yam, C W, Tsang, T Y Y, Lai   +7 more
openaire   +2 more sources

TGF-β2 levels in the aqueous humor are elevated in the second eye of high myopia within two weeks after sequential cataract surgery

Scientific Reports, 2022
Transforming growth factor-β (TGF-β) is the critical regulator of physiological and pathological conditions in lens. The TGF-β signaling pathway is closely associated with high myopia patients.
Weijia Yan, Yaping Zhang, Junguo Cao, Hong Yan   +3 more
doaj   +1 more source