Results 171 to 180 of about 981,501 (315)

Oligodendroglioma: pathology, molecular mechanisms and markers. [PDF]

Acta Neuropathol, 2015
Wesseling P, van den Bent M, Perry A.
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Research Progress on Pathology, Molecular Mechanisms, and Intervention Strategies of Cognitive Dysfunction Associated with Type 2 Diabetes. [PDF]

Int J Gen Med
Zhou H, Ran Y, Jiang Y, Li R.
europepmc   +1 more source

Zika virus: An update on epidemiology, pathology, molecular biology, and animal model. [PDF]

J Med Virol, 2016
Ramos da Silva S, Gao SJ.
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The Emotional Anatomy of Diagnosis: A Medical Humanities Approach to Empathy in Pathology

Background/Objectives: Pathology is often perceived as a technical medical specialty that lacks direct contact with the patient. However, oncological histopathological diagnosis requires a high degree of moral and emotional responsibility.
Maria-Elena Cocuz, Martin Manole, Adrian-Horațiu Sabău, Ovidiu Simion Cotoi, Dorina Maria Pașca, Alexandru-Constantin Ioniță, Maria Cătălina Popelea, Giordano Altarozzi, Raluca Niculescu, Maria Tătar-Dan, Iuliu Gabriel Cocuz   +10 more
core   +1 more source

Osteoarthritis: multitissue pathology, molecular mechanisms, clinical management, and emerging precision and regenerative therapies. [PDF]

Front Pharmacol
Qiu L, Alhaskawi A, Moqbel SAA.
europepmc   +1 more source

Pilocytic astrocytoma: pathology, molecular mechanisms and markers. [PDF]

Acta Neuropathol, 2015
Collins VP, Jones DT, Giannini C.
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Carcinosarcoma of the Endometrium-Pathology, Molecular Landscape and Novel Therapeutic Approaches. [PDF]

Medicina (Kaunas)
Kostov S, Kornovski Y, Ivanova V, Dzhenkov D, Metodiev D, Wafa M, Ivanova Y, Slavchev S, Tsoneva E, Yordanov A.   +9 more
europepmc   +1 more source