Results 121 to 130 of about 2,327,306 (258)

Milestones in the evolution of pathology in Malta [PDF]

, 1996
This book offers a brief sketch of events in chronological sequence that mark the rise of the science of pathology in Malta over the past three hundred years.
Cassar, Paul, University of Malta. Department of Pathology   +1 more
core  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Oral and maxillofacial pathology in Latin America and the Caribbean: a comprehensive survey of recognition, training, and practice [PDF]

Trabajo elaborado por otros veintiocho autores.Background: Oral and maxillofacial pathology (OMFP) is a dental specialty that studies the causes, processes, and effects of diseases in the oral and maxillofacial area, while also contributing to diagnosis ...
Santos-Silva, Alan Roger, González-Pérez, Leonor Victoria, Bologna-Molina, Ronell   +2 more
core   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

Basaloid squamous carcinoma of the oral cavity. Report of a case

, 1993
A case of basaloid squamous carcinoma that involves the posterior buccal mucosa is described. The major histopathologic feature is a carcinoma with a basaloid pattern in association with squamous differentiation.
Moraes, Norberto Perri, Biazolla, Eder Ricardo, de Araújo, Vera Cavalcanti, Melhado, Ronaldo Maia, Furuse, Takeo Adhemar   +4 more
core   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Profile and satisfaction of oral pathology/medicine postgraduates: a national multicenter study

BACKGROUND: This study aimed to evaluate the profile and professional satisfaction of postgraduate students in Oral Pathology (OP) and Oral Medicine (OM) enrolled in Stricto sensu programs across various Brazilian institutions.
Duarte, \uc1rlen Almeida, Bonan, Paulo Rogério Ferreti, Lopes, Marcio Ajudarte, Martelli, Daniella Reis Barbosa, Almeida, Janete Dias [UNESP], Maia-Lima, Marcos Paulo, Almeida, Janete Dias, Alves, F\ue1bio de Abreu, Nascimento, João Pedro Santos, Duarte, Árlen Almeida, dos Santos, Jean Nunes, Trezena, Samuel, de Oliveira, Fabr\uedcio Emanuel Soares, Martelli-Júnior, Hercílio, Bonan, Paulo Rog\ue9rio Ferreti, de Almeida Freitas, Roseana, Nascimento, Jo\ue3o Pedro Santos, Martelli-J\ufanior, Herc\uedlio, Ferreira, Luiz Miguel, Freitas, Roseana de Almeida, de Aguiar, Maria Cassia Ferreira, de Oliveira, Fabrício Emanuel Soares, de Abreu Alves, Fábio   +22 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Critical Role of P27KIP1, P21CIP1/WAF1 and Cyclin D1 in the Antiproliferative Effect of Tyrosine Kinase Inhibitor(ZD1839) for Epidermal Growth Factor Receptor in the Human Oral Squamous Cell Carcinoma

, 2006
It is well known that the imbalance between epithelial cell growth and inhibitor factors may cause human epithelial cancer. Over-expression of the epidermal growth factor receptor(EGFR) has been implicated in the development of oral squamous cell ...
김진, 이은주
core