Results 151 to 160 of about 369,599 (261)

Porphyromonas gingivalis disrupts hippocampal circadian clock via PI3K/AKT pathway, exacerbating Alzheimer-like pathology. [PDF]

Alzheimers Dement
Huang C, Cai Q, Feng Z, Zhang C, Luo Z, Cheng X, Wu H.   +6 more
europepmc   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Revisiting the grand challenges in oral cancers: advances in biomarkers and treatment strategies. [PDF]

Front Oral Health
Coletta RD, Al-Samadi A, Yeudall WA, Salo T.   +3 more
europepmc   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Survival Trends Associated With Histopathological Risk Factors in Oral Squamous Cell Carcinoma

International Journal of Dentistry
Shyam Sthanukrishnan, Smitha Sammith Shetty, Chetana Chandrashekar, Deepak Nayak, Raghu Radhakrishnan   +4 more
doaj   +1 more source

The Role of Family Pathology in Noma: A Scoping Review of Household-Level Risk Factors in Sub-Saharan Africa. [PDF]

J Trop Med
Bala M, Abdullahi MAS, Braimah RO, Taiwo AO, Suleiman IK, Karagozoglu KH.   +5 more
europepmc   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Forensic dentistry - Present and future. [PDF]

Bioinformation
Khatri S, Deshpande SM, Rebello P, Sinha N, Khare P, Vidya B, Goel D.   +6 more
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

A Curious Gingival Erosion: A Rare Oral Manifestation of Fixed Drug Eruption. [PDF]

Cureus
Lutz CM, Le Pelletier de Glatigny F, Ejeil AL.   +2 more
europepmc   +1 more source