Results 191 to 200 of about 370,051 (261)

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

The Relative Frequency of Oral Lichen Planus and Oral Lichenoid Lesions in a New Zealand Population Diagnosed at a Specialist Reference Centre. [PDF]

Clin Exp Dent Res
Sameera A, Nizar MABM, Hussaini HM, Cooper P, Rich AM, Seo B.   +5 more
europepmc   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Psychological disorders and their influence on the development of periodontal disease in adolescents. A systematic review. [PDF]

Med Oral Patol Oral Cir Bucal
Alagarda-Lauwers B, Peñarrubia-Martínez L, García-Selva M, González-Angulo E, Cases-Sánchez A, Fons-Badal C.   +5 more
europepmc   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Bridging Medicine and Dentistry Through Clinical Pathology: A Call for Integration. [PDF]

Sage Open Pathol
Maruyama T.
europepmc   +1 more source

Management of Peripheral Cemento-Ossifying Fibroma. [PDF]

Cureus
Sabesan M, Rajan ST, Nirmala V, Ravindran DM, Sharon B.   +4 more
europepmc   +1 more source

Dental Calculus Deposition: Correlation With Salivary Statherin and Calcium Levels

International Journal of Dentistry
Pranjali Hase, Vandana Shah, Shilpa Gunjal, Bhari Sharanesha Manjunatha, Deepak Gowda Sadashivappa Pateel   +4 more
doaj   +1 more source

Therapeutic synergy in long-standing plasma cell gingivitis: integrating photobiomodulation and immunomodulatory management. [PDF]

An Bras Dermatol
Hurtado J, Meza V, Valenzuela F, Mujica I.   +3 more
europepmc   +1 more source