Results 81 to 90 of about 591,590 (263)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesIntroduction: Mucormycosis is a severe infection caused by fungi of the order Mucorales, characterized by vascular invasion and tissue necrosis. Clinical forms include rhino-cerebral, pulmonary, cutaneous, disseminated, and other rare presentations ...
Carolina Ventura Hawerroth +4 more
doaj +1 more source
Comparison of Diagnostic Concordance between Glass and Digitally Scanned Pathology Slides in Hospitals of Shiraz University of Medical Sciences [PDF]
مجله علوم پزشکی صدراIntroduction: The use of digital imaging in pathology has transformed this traditional field into what is now termed digital pathology. Digital pathology plays an important role in modern clinical practice and is increasingly viewed as a technological ...
Neda Soleimani +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The Breast JournalConclusion: IGM is a benign, often self-limiting disorder. However, it mimics malignancy in 60% cases, and histology clinches the diagnosis. We report the efficacy of steroid-free management of IGM with immunomodulatory herbal origin phytopharmaceutical ...
Ankita Das Sheth +11 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Safe Surgical Pathology Material Management in the Operating Room
Sağlık ve Hemşirelik Yönetimi Dergisi, 2017 Background: Surgical pathology material management (SPMM) is creating a important part of patient safety in operating room. Removed from patients surgical pathology materials (SPM) play a key role for diagnosis and correct treatment.
Semra Bülbüloğlu +3 more
doaj +1 more source
The surgical pathology of bilharziasis.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000 Click on the link to view.
openaire +2 more sources