Results 261 to 270 of about 3,901,788 (321)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Recent trends in gene-targeted therapies and their influence on surgical decision-making in rheumatoid arthritis affecting the hands, feet, and ankles. [PDF]

Front Med (Lausanne)
Du X, Yu X, Ou X, Cheng D, Zheng C, Shi S.   +5 more
europepmc   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Validation of Artificial Intelligence-enhanced Stimulated Raman Histopathology for Intraoperative Margin Assessment During Robot-assisted Radical Prostatectomy: Preliminary Results from the ROBOSPEC Study. [PDF]

Eur Urol Open Sci
Özkan A, Schröder KM, Bronsert P, Franz J, Glienke M, Sigle A, Beck J, Werner M, Gratzke C, Straehle J, Taneja SS, Mannas MP, Liakos N.   +12 more
europepmc   +1 more source

Primary poorly differentiated enteric-type adenocarcinoma of the thymus with characteristic intracytoplasmic vacuoles on cytology. [PDF]

Respir Med Case Rep
Tachibana M, Hirota T, Uehara M, Tsukamoto K, Ishikawa R, Tsuchida T.   +5 more
europepmc   +1 more source

CBCT-Assisted Microsurgical Management of Dual Periapical Lesions Involving Vital and Previously Endodontically Treated Maxillary Molars: A Case Report. [PDF]

Clin Case Rep
Asgary S.
europepmc   +1 more source

Diagnosis of gallbladder villous tubular adenoma with high-grade intraepithelial neoplasia via peroral endoscopic choledochoscopy: a rare case of an elderly patient. [PDF]

Endoscopy
Zhang J.
europepmc   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Combined transcranial and endoscopic endonasal approach for anterior skull base meningiomas: approach and reconstruction strategies. [PDF]

Neurosurg Focus Video
Whipple-Bones S, Tabor MH, Magill ST, Terrell D, Beer-Furlan A.   +4 more
europepmc   +1 more source