Results 41 to 50 of about 602,519 (263)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Communicating Uncertainty in Surgical Pathology Reports

Academic Pathology, 2016
In order to document perceptions of text comments appearing in surgical pathology reports, questionnaires were distributed to 4 groups of caregivers: university staff pathologists, resident pathologists, faculty clinicians (other than pathologists), and ...
Erika Bracamonte MD, Blake A. Gibson BS, BA, Robert Klein MD, Elizabeth A. Krupinski PhD, FATA, FSIIM, FSPIE, Ronald S. Weinstein MD, FCAP, FATA   +4 more
doaj   +1 more source

Minimally invasive techniques in thymic surgery (review of literature)

Вестник хирургии имени И.И. Грекова, 2021
We carried out the systematic review of the domestic and foreign literature focusing on surgical treatment of patients with thymic pathology. Special attention was paid to the discussion of the advantages of minimally invasive surgery, particularly ...
O. V. Pikin, A. B. Ryabov, D. Ye. Martinova, Z. M. Salimov   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Endometriosis – especially surgical pathology?

Гинекология, 2013
The application of the combined hormonal contraceptives in the preventive maintenance of disease and the successful fight with the most common clinical manifestations of endometriosis, namely, with the syndrome EAPP (endometriosis associated pelvic pain):
A L Tikhomirov
doaj  

Ovarian mucinous tumors with mural nodules: immunohistochemical and molecular analysis of 3 cases

Diagnostic Pathology, 2020
Background Primary ovarian mucinous tumors with mural nodules are very rare. The histogenesis of the mural nodules remains unclear. Methods We investigated the clincopathological and molecular features in 3 cases with mural nodules. Results Patient 1 was
Ying Shao, Qin Liu, Haiyan Shi, Bingjian Lu   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

EFFICIENCY OF COMPLEX THERAPY OF PREMATURE WITH SURGICAL PATHOLOGY

Кубанский научный медицинский вестник, 2017
Aim. Estimate the efficiency of improved complex therapy of premature with surgical pathology.Materials and methods. 374 medical histories of premature infants were studied.
A. F. Komarov, E. I. Kleshenko, D. A. Kayumova, M. P. Yakovenko, U. B. Nekhoroshkina, M. G. Kulagina, V. I. Alekhina, E. V. Borovikova, E. P. Apalkova   +8 more
doaj   +1 more source