Results 81 to 90 of about 24,293 (183)
Association between neoadjuvant paclitaxel dose intensity and outcomes in early triple-negative and HER2-positive breast cancer: a real-world data analysis
ESMO Real World Data and Digital OncologyBackground: Reduction of paclitaxel dose intensity (PDI) is frequent during neoadjuvant treatment of high-risk early triple-negative (TN) and human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC), due to toxicity.C. van Marcke, K. Pogoda, H. Fenton, M. Vallet, G. Plavc, M. Borges, H. Yousuf, E. Dumas, M. Berliere, G. Ciliberto, F.P. Duhoux, V. Fano, P. Hall, K. Kolenc Mokotar, L. Lopes Conceicao, F. Pereira, A. Škoporc, A. Thomas, G. Tramonti, M.R. van Bockstal, P. Vici, M. Uher, E. Krasniqi +22 moredoaj +1 more sourceUnraveling genetic load dynamics during biological invasion: insights from two invasive insect species
Peer Community JournalMany invasive species undergo a significant reduction in genetic diversity, i.e. a genetic bottleneck, in the early stages of invasion. However, this reduction does not necessarily prevent them from achieving considerable ecological success and becoming ...Lombaert, Eric, Blin, Aurélie, Porro, Barbara, Guillemaud, Thomas, Bernal, Julio S., Chang, Gary, Kirichenko, Natalia, Sappington, Thomas W., Toepfer, Stefan, Deleury, Emeline +9 moredoaj +1 more sourceMIAWARE Software:3D Medical Image Analysis with Automated Reporting Engine and Ontology-based Search [PDF]
, 2008 which was designed and developed for doctor/radiologist assistance. It allows to analyze an image stack from computed axial tomography scan of lungs (thorax) and, at the same time, to mark all pathologies on images and report their characteristics.Castro, Miguel, Dias, Paulo, Janicki, Marcin, Pereira, Oscar N. M., Wilkowski, Bartlomiej +4 morecore +2 more sourcesAssociations of autozygosity with a broad range of human phenotypes
Nature Communications, 2019 Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is ...David W Clark, Yukinori Okada, Kristjan H S Moore, Dan Mason, Nicola Pirastu, Ilaria Gandin, Hannele Mattsson, Catriona L K Barnes, Kuang Lin, Jing Hua Zhao, Patrick Deelen, Rebecca Rohde, Claudia Schurmann, Xiuqing Guo, Franco Giulianini, Weihua Zhang, Carolina Medina-Gomez, Robert Karlsson, Yanchun Bao, Traci M Bartz, Clemens Baumbach, Ginevra Biino, Matthew J Bixley, Marco Brumat, Jin-Fang Chai, Tanguy Corre, Diana L Cousminer, Annelot M Dekker, David A Eccles, Kristel R van Eijk, Christian Fuchsberger, He Gao, Marine Germain, Scott D Gordon, Hugoline G de Haan, Sarah E Harris, Edith Hofer, Alicia Huerta-Chagoya, Catherine Igartua, Iris E Jansen, Yucheng Jia, Tim Kacprowski, Torgny Karlsson, Marcus E Kleber, Shengchao Alfred Li, Ruifang Li-Gao, Anubha Mahajan, Koichi Matsuda, Karina Meidtner, Weihua Meng, May E Montasser, Peter J van der Most, Matthias Munz, Teresa Nutile, Teemu Palviainen, Gauri Prasad, Rashmi B Prasad, Tallapragada Divya Sri Priyanka, Federica Rizzi, Erika Salvi, Bishwa R Sapkota, Daniel Shriner, Line Skotte, Melissa C Smart, Albert Vernon Smith, Ashley van der Spek, Cassandra N Spracklen, Rona J Strawbridge, Salman M Tajuddin, Stella Trompet, Constance Turman, Niek Verweij, Clara Viberti, Lihua Wang, Helen R Warren, Robyn E Wootton, Lisa R Yanek, Jie Yao, Noha A Yousri, Wei Zhao, Adebowale A Adeyemo, Saima Afaq, Carlos Alberto Aguilar-Salinas, Masato Akiyama, Matthew L Albert, Matthew A Allison, Maris Alver, Tin Aung, Fereidoun Azizi, Amy R Bentley, Heiner Boeing, Eric Boerwinkle, Judith B Borja, Gert J de Borst, Erwin P Bottinger, Linda Broer, Harry Campbell, Stephen Chanock, Miao-Li Chee, Guanjie Chen, Yii-Der I Chen, Zhengming Chen, Yen-Feng Chiu, Massimiliano Cocca, Francis S Collins, Maria Pina Concas, Janie Corley, Giovanni Cugliari, Rob M van Dam, Anna Damulina, Maryam S Daneshpour, Felix R Day, Graciela E Delgado, Klodian Dhana, Alexander S F Doney, Marcus Dörr, Ayo P Doumatey, Nduna Dzimiri, S Sunna Ebenesersdóttir, Joshua Elliott, Paul Elliott, Ralf Ewert, Janine F Felix, Krista Fischer, Barry I Freedman, Giorgia Girotto, Anuj Goel, Martin Gögele, Mark O Goodarzi, Mariaelisa Graff, Einat Granot-Hershkovitz, Francine Grodstein, Simonetta Guarrera, Daniel F Gudbjartsson, Kamran Guity, Bjarni Gunnarsson, Yu Guo, Saskia P Hagenaars, Christopher A Haiman, Avner Halevy, Tamara B Harris, Mehdi Hedayati, David A van Heel, Makoto Hirata, Imo Höfer, Chao Agnes Hsiung, Jinyan Huang, Yi-Jen Hung, M Arfan Ikram, Anuradha Jagadeesan, Pekka Jousilahti, Yoichiro Kamatani, Masahiro Kanai, Nicola D Kerrison, Thorsten Kessler, Kay-Tee Khaw, Chiea Chuen Khor, Dominique P V de Kleijn, Woon-Puay Koh, Ivana Kolcic, Peter Kraft, Bernhard K Krämer, Zoltán Kutalik, Johanna Kuusisto, Claudia Langenberg, Lenore J Launer, Deborah A Lawlor, I-Te Lee, Wen-Jane Lee, Markus M Lerch, Liming Li, Jianjun Liu, Marie Loh, Stephanie J London, Stephanie Loomis, Yingchang Lu, Jian’an Luan, Reedik Mägi, Ani W Manichaikul, Paolo Manunta, Gísli Másson, Nana Matoba, Xue W Mei, Christa Meisinger, Thomas Meitinger, Massimo Mezzavilla, Lili Milani, Iona Y Millwood, Yukihide Momozawa, Amy Moore, Pierre-Emmanuel Morange, Hortensia Moreno-Macías, Trevor A Mori, Alanna C Morrison, Taulant Muka, Yoshinori Murakami, Alison D Murray, Renée de Mutsert, Josyf C Mychaleckyj, Mike A Nalls, Matthias Nauck, Matt J Neville, Ilja M Nolte, Ken K Ong, Lorena Orozco, Sandosh Padmanabhan, Gunnar Pálsson, James S Pankow, Cristian Pattaro, Alison Pattie, Ozren Polasek, Neil Poulter, Peter P Pramstaller, Lluis Quintana-Murci, Katri Räikkönen, Sarju Ralhan, Dabeeru C Rao, Wouter van Rheenen, Stephen S Rich, Paul M Ridker, Cornelius A Rietveld, Antonietta Robino, Frank J A van Rooij, Daniela Ruggiero, Yasaman Saba, Charumathi Sabanayagam, Maria Sabater-Lleal, Cinzia Felicita Sala, Veikko Salomaa, Kevin Sandow, Helena Schmidt, Laura J Scott, William R Scott, Bahareh Sedaghati-Khayat, Bengt Sennblad, Jessica van Setten, Peter J Sever, Wayne H-H Sheu, Yuan Shi, Smeeta Shrestha, Sharvari Rahul Shukla, Jon K Sigurdsson, Timo Tonis Sikka, Jai Rup Singh, Blair H Smith, Alena Stančáková, Alice Stanton, John M Starr, Lilja Stefansdottir, Leon Straker, Patrick Sulem, Gardar Sveinbjornsson, Morris A Swertz, Adele M Taylor, Kent D Taylor, Natalie Terzikhan, Yih-Chung Tham, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Annika Tillander, Russell P Tracy, Teresa Tusié-Luna, Ioanna Tzoulaki, Simona Vaccargiu, Jagadish Vangipurapu, Jan H Veldink, Veronique Vitart, Uwe Völker, Eero Vuoksimaa, Salma M Wakil, Melanie Waldenberger, Gurpreet S Wander, Ya Xing Wang, Nicholas J Wareham, Sarah Wild, Chittaranjan S Yajnik, Jian-Min Yuan, Lingyao Zeng, Liang Zhang, Jie Zhou, Najaf Amin, Folkert W Asselbergs, Stephan J L Bakker, Diane M Becker, Benjamin Lehne, David A Bennett, Leonard H van den Berg, Sonja I Berndt, Dwaipayan Bharadwaj, Lawrence F Bielak, Murielle Bochud, Mike Boehnke, Claude Bouchard, Jonathan P Bradfield, Jennifer A Brody, Archie Campbell, Shai Carmi, Mark J Caulfield, David Cesarini, John C Chambers, Giriraj Ratan Chandak, Ching-Yu Cheng, Marina Ciullo, Marilyn Cornelis, Daniele Cusi, George Davey Smith, Ian J Deary, Rajkumar Dorajoo, Cornelia M van Duijn, David Ellinghaus, Jeanette Erdmann, Johan G Eriksson, Evangelos Evangelou, Michele K Evans, Jessica D Faul, Bjarke Feenstra, Mary Feitosa, Sylvain Foisy, Andre Franke, Yechiel Friedlander, Paolo Gasparini, Christian Gieger, Clicerio Gonzalez, Philippe Goyette, Struan F A Grant, Lyn R Griffiths, Leif Groop, Vilmundur Gudnason, Ulf Gyllensten, Hakon Hakonarson, Anders Hamsten, Pim van der Harst, Chew-Kiat Heng, Andrew A Hicks, Hagit Hochner, Heikki Huikuri, Steven C Hunt, Vincent W V Jaddoe, Philip L De Jager, Magnus Johannesson, Åsa Johansson, Jost B Jonas, J Wouter Jukema, Juhani Junttila, Jaakko Kaprio, Sharon L. R. Kardia, Fredrik Karpe, Meena Kumari, Markku Laakso, Sander W van der Laan, Jari Lahti, Matthias Laudes, Rodney A Lea, Wolfgang Lieb, Thomas Lumley, Nicholas G Martin, Winfried März, Giuseppe Matullo, Mark I McCarthy, Sarah E Medland, Tony R Merriman, Andres Metspalu, Brian F Meyer, Karen L Mohlke, Grant W Montgomery, Dennis Mook-Kanamori, Patricia B Munroe, Kari E North, Dale R Nyholt, Jeffery R O’connell, Carole Ober, Albertine J Oldehinkel, Walter Palmas, Colin Palmer, Gerard G Pasterkamp, Etienne Patin, Craig E Pennell, Louis Perusse, Patricia A Peyser, Mario Pirastu, Tinca J. C. Polderman, David J Porteous, Danielle Posthuma, Bruce M Psaty, John D Rioux, Fernando Rivadeneira, Charles Rotimi, Jerome I Rotter, Igor Rudan, Hester M Den Ruijter, Dharambir K Sanghera, Naveed Sattar, Reinhold Schmidt, Matthias B Schulze, Heribert Schunkert, Robert A Scott, Alan R Shuldiner, Xueling Sim, Neil Small, Jennifer A Smith, Nona Sotoodehnia, E-Shyong Tai, Alexander Teumer, Nicholas J Timpson, Daniela Toniolo, David-Alexandre Tregouet, Tiinamaija Tuomi, Peter Vollenweider, Carol A Wang, David R Weir, John B Whitfield, Cisca Wijmenga, Tien-Yin Wong, John Wright, Jingyun Yang, Lei Yu, Babette S Zemel, Alan B Zonderman, Markus Perola, Patrik K. E. Magnusson, André G Uitterlinden, Jaspal S Kooner, Daniel I Chasman, Ruth J. F. Loos, Nora Franceschini, Lude Franke, Chris S Haley, Caroline Hayward, Robin G Walters, John R. B. Perry, Tōnu Esko, Agnar Helgason, Kari Stefansson, Peter K Joshi, Michiaki Kubo, James F Wilson +435 moredoaj +1 more sourceWP 111 - Health workforce remuneration: Comparing wage levels, ranking and dispersion of 16 occupational groups in 20 countries using survey data [PDF]
This article focuses on remuneration in the Human Resources for Health (HRH), comparing wage levels, ranking and dispersion of 16 HRH occupations in 20 countries (Argentina, Belarus, Belgium, Brazil, Chile, Colombia, Czech Republic, Finland, Germany ...Danny Vries, Kea Tijdenscore A preexisting rare PIK3CA e545k subpopulation confers clinical resistance to MEK plus CDK4/6 inhibition in NRAS melanoma and is dependent on S6K1 signaling [PDF]
, 2018 Combined MEK and CDK4/6 inhibition (MEKi + CDK4i) has shown promising clinical outcomes in patients with NRAS- mutant melanoma. Here, we interrogated longitudinal biopsies from a patient who initially responded to MEKi + CDK4i therapy but subsequently ...Amaria, Rodabe N., Aplin, Andrew A., Carapeto, Fernando C.L., Chen, Merry, Chen, Pei-Ling, Davies, Michael A., Duose, Dzifa Y., Futreal, P. Andrew, Kwong, Lawrence N., Lazar, Alexander J., Li, Jun, Liang, Roger J., Liu, Mingguang, McQuade, Jennifer L., Roh, Whijae, Romano, Gabriele, Song, Ping, Teh, Jessica L.F., Wargo, Jennifer A., Zhang, David Y., Zhang, Jianhua +20 morecore +1 more sourceTowards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge
Nature CommunicationsComputational competitions are the standard for benchmarking medical image analysis algorithms, but they typically use small curated test datasets acquired at a few centers, leaving a gap to the reality of diverse multicentric patient data.Maximilian Zenk, Ujjwal Baid, Sarthak Pati, Akis Linardos, Brandon Edwards, Micah Sheller, Patrick Foley, Alejandro Aristizabal, David Zimmerer, Alexey Gruzdev, Jason Martin, Russell T. Shinohara, Annika Reinke, Fabian Isensee, Santhosh Parampottupadam, Kaushal Parekh, Ralf Floca, Hasan Kassem, Bhakti Baheti, Siddhesh Thakur, Verena Chung, Kaisar Kushibar, Karim Lekadir, Meirui Jiang, Youtan Yin, Hongzheng Yang, Quande Liu, Cheng Chen, Qi Dou, Pheng-Ann Heng, Xiaofan Zhang, Shaoting Zhang, Muhammad Irfan Khan, Mohammad Ayyaz Azeem, Mojtaba Jafaritadi, Esa Alhoniemi, Elina Kontio, Suleiman A. Khan, Leon Mächler, Ivan Ezhov, Florian Kofler, Suprosanna Shit, Johannes C. Paetzold, Timo Loehr, Benedikt Wiestler, Himashi Peiris, Kamlesh Pawar, Shenjun Zhong, Zhaolin Chen, Munawar Hayat, Gary Egan, Mehrtash Harandi, Ece Isik Polat, Gorkem Polat, Altan Kocyigit, Alptekin Temizel, Anup Tuladhar, Lakshay Tyagi, Raissa Souza, Nils D. Forkert, Pauline Mouches, Matthias Wilms, Vishruth Shambhat, Akansh Maurya, Shubham Subhas Danannavar, Rohit Kalla, Vikas Kumar Anand, Ganapathy Krishnamurthi, Sahil Nalawade, Chandan Ganesh, Ben Wagner, Divya Reddy, Yudhajit Das, Fang F. Yu, Baowei Fei, Ananth J. Madhuranthakam, Joseph Maldjian, Gaurav Singh, Jianxun Ren, Wei Zhang, Ning An, Qingyu Hu, Youjia Zhang, Ying Zhou, Vasilis Siomos, Giacomo Tarroni, Jonathan Passerrat-Palmbach, Ambrish Rawat, Giulio Zizzo, Swanand Ravindra Kadhe, Jonathan P. Epperlein, Stefano Braghin, Yuan Wang, Renuga Kanagavelu, Qingsong Wei, Yechao Yang, Yong Liu, Krzysztof Kotowski, Szymon Adamski, Bartosz Machura, Wojciech Malara, Lukasz Zarudzki, Jakub Nalepa, Yaying Shi, Hongjian Gao, Salman Avestimehr, Yonghong Yan, Agus S. Akbar, Ekaterina Kondrateva, Hua Yang, Zhaopei Li, Hung-Yu Wu, Johannes Roth, Camillo Saueressig, Alexandre Milesi, Quoc D. Nguyen, Nathan J. Gruenhagen, Tsung-Ming Huang, Jun Ma, Har Shwinder H. Singh, Nai-Yu Pan, Dingwen Zhang, Ramy A. Zeineldin, Michal Futrega, Yading Yuan, Gian Marco Conte, Xue Feng, Quan D. Pham, Yong Xia, Zhifan Jiang, Huan Minh Luu, Mariia Dobko, Alexandre Carré, Bair Tuchinov, Hassan Mohy-ud-Din, Saruar Alam, Anup Singh, Nameeta Shah, Weichung Wang, Chiharu Sako, Michel Bilello, Satyam Ghodasara, Suyash Mohan, Christos Davatzikos, Evan Calabrese, Jeffrey Rudie, Javier Villanueva-Meyer, Soonmee Cha, Christopher Hess, John Mongan, Madhura Ingalhalikar, Manali Jadhav, Umang Pandey, Jitender Saini, Raymond Y. Huang, Ken Chang, Minh-Son To, Sargam Bhardwaj, Chee Chong, Marc Agzarian, Michal Kozubek, Filip Lux, Jan Michálek, Petr Matula, Miloš Ker^kovský, Tereza Kopr^ivová, Marek Dostál, Václav Vybíhal, Marco C. Pinho, James Holcomb, Marie Metz, Rajan Jain, Matthew D. Lee, Yvonne W. Lui, Pallavi Tiwari, Ruchika Verma, Rohan Bareja, Ipsa Yadav, Jonathan Chen, Neeraj Kumar, Yuriy Gusev, Krithika Bhuvaneshwar, Anousheh Sayah, Camelia Bencheqroun, Anas Belouali, Subha Madhavan, Rivka R. Colen, Aikaterini Kotrotsou, Philipp Vollmuth, Gianluca Brugnara, Chandrakanth J. Preetha, Felix Sahm, Martin Bendszus, Wolfgang Wick, Abhishek Mahajan, Carmen Balaña, Jaume Capellades, Josep Puig, Yoon Seong Choi, Seung-Koo Lee, Jong Hee Chang, Sung Soo Ahn, Hassan F. Shaykh, Alejandro Herrera-Trujillo, Maria Trujillo, William Escobar, Ana Abello, Jose Bernal, Jhon Gómez, Pamela LaMontagne, Daniel S. Marcus, Mikhail Milchenko, Arash Nazeri, Bennett Landman, Karthik Ramadass, Kaiwen Xu, Silky Chotai, Lola B. Chambless, Akshitkumar Mistry, Reid C. Thompson, Ashok Srinivasan, J. Rajiv Bapuraj, Arvind Rao, Nicholas Wang, Ota Yoshiaki, Toshio Moritani, Sevcan Turk, Joonsang Lee, Snehal Prabhudesai, John Garrett, Matthew Larson, Robert Jeraj, Hongwei Li, Tobias Weiss, Michael Weller, Andrea Bink, Bertrand Pouymayou, Sonam Sharma, Tzu-Chi Tseng, Saba Adabi, Alexandre Xavier Falcão, Samuel B. Martins, Bernardo C. A. Teixeira, Flávia Sprenger, David Menotti, Diego R. Lucio, Simone P. Niclou, Olivier Keunen, Ann-Christin Hau, Enrique Pelaez, Heydy Franco-Maldonado, Francis Loayza, Sebastian Quevedo, Richard McKinley, Johannes Slotboom, Piotr Radojewski, Raphael Meier, Roland Wiest, Johannes Trenkler, Josef Pichler, Georg Necker, Andreas Haunschmidt, Stephan Meckel, Pamela Guevara, Esteban Torche, Cristobal Mendoza, Franco Vera, Elvis Ríos, Eduardo López, Sergio A. Velastin, Joseph Choi, Stephen Baek, Yusung Kim, Heba Ismael, Bryan Allen, John M. Buatti, Peter Zampakis, Vasileios Panagiotopoulos, Panagiotis Tsiganos, Sotiris Alexiou, Ilias Haliassos, Evangelia I. Zacharaki, Konstantinos Moustakas, Christina Kalogeropoulou, Dimitrios M. Kardamakis, Bing Luo, Laila M. Poisson, Ning Wen, Martin Vallières, Mahdi Ait Lhaj Loutfi, David Fortin, Martin Lepage, Fanny Morón, Jacob Mandel, Gaurav Shukla, Spencer Liem, Gregory S. Alexandre, Joseph Lombardo, Joshua D. Palmer, Adam E. Flanders, Adam P. Dicker, Godwin Ogbole, Dotun Oyekunle, Olubunmi Odafe-Oyibotha, Babatunde Osobu, Mustapha Shu’aibu Hikima, Mayowa Soneye, Farouk Dako, Adeleye Dorcas, Derrick Murcia, Eric Fu, Rourke Haas, John A. Thompson, David Ryan Ormond, Stuart Currie, Kavi Fatania, Russell Frood, Amber L. Simpson, Jacob J. Peoples, Ricky Hu, Danielle Cutler, Fabio Y. Moraes, Anh Tran, Mohammad Hamghalam, Michael A. Boss, James Gimpel, Deepak Kattil Veettil, Kendall Schmidt, Lisa Cimino, Cynthia Price, Brian Bialecki, Sailaja Marella, Charles Apgar, Andras Jakab, Marc-André Weber, Errol Colak, Jens Kleesiek, John B. Freymann, Justin S. Kirby, Lena Maier-Hein, Jake Albrecht, Peter Mattson, Alexandros Karargyris, Prashant Shah, Bjoern Menze, Klaus Maier-Hein, Spyridon Bakas +346 moredoaj +1 more source
