Results 71 to 80 of about 1,910,959 (261)
Current Issues in Molecular BiologySepsis is a life-threatening condition characterized by a dysregulated host response to infection, leading to multi-organ dysfunction. Toll-like receptor signaling via MYD88- and TRIF-dependent pathways plays a central role in this process; however, its ...
Maria Erodotou +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen +5 more
wiley +1 more source
Pest risk assessment of African Leucinodes species for the European Union
EFSA JournalFollowing a request from the European Commission, the EFSA Panel on Plant Health performed a quantitative risk assessment for the EU of African Leucinodes species (Lepidoptera: Crambidae), which are fruit and shoot borers, especially of eggplant type ...
EFSA Panel on Plant Health (PLH) +30 more
doaj +1 more source
Care pathway for the elderly: detailing the model
Revista Brasileira de Geriatria e Gerontologia, 2016 Greater knowlegde of patient history among health professionals leads to improved results. This is how the contemporary and resolutive models of care recommended by the most important national and international health agencies work.
Renato Veras, Martha Oliveira
doaj +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
HeliyonThis research examines the impacts of climate change and socio-economic variables on the hydrological cycle, reservoir water management, and hydropower capacity at the Gezhouba Dam. The Gezhouba Dam serves as a crucial hydroelectric power station and dam,
Chenyang Xiao, Mohammad Mohammaditab
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
LIFE.PTML Model Development Targeting Calmodulin Pathway Proteins
Chemistry ProceedingsDeveloping predictive models for drug efficacy is challenged by the complexity and heterogeneity of bioassay data. Here, we present LIFE.PTML, which is a methodology integrating drug Lifecycle (L), Information Fusion (IF), Encoding (E), Perturbation ...
Maider Baltasar-Marchueta +4 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source