Results 131 to 140 of about 969,785 (263)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pathways to care and service preferences, and experiences of women who self-manage abortion through community pharmacies in two counties of Kenya. [PDF]

BMJ Glob Health
Obare F, Sigu SB, Liambila W, Otieno B, Nyamwaro L, Shellenberg K.   +5 more
europepmc   +1 more source

Tuberculosis Pathways to Care and Transmission of Multidrug Resistance in India. [PDF]

Am J Respir Crit Care Med, 2022
Atre SR, Jagtap JD, Faqih MI, Dumbare YK, Sawant TU, Ambike SL, Bhawalkar JS, Bharaswadkar SK, Jogewar PK, Adkekar RS, Hodgar BP, Jadhav V, Mokashi ND, Golub JE, Dixit A, Farhat MR.   +15 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Lived experiences of missing with dementia and pathways to care: a qualitative study of carers' and professionals' perspectives. [PDF]

Age Ageing
Leung P, Lye V, Kwok HT, Fong L, Orgeta V.   +4 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Current Pathways of Care Continue to Fail Those With a Diagnosis of Endometriosis. [PDF]

BJOG
Vincent K, Horne AW.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

"Pathways to care among antenatal women in South India - A sequential explanatory mixed-method study". [PDF]

J Family Med Prim Care
Jarain VZL, Ramakrishnan J, Ravel V, Purushothaman P, Susila T, Banu Z, Chinnakali P.   +6 more
europepmc   +1 more source

Reorienting the focus from an individual to a community-level lens to improve the pathways through care for early psychosis in the United States. [PDF]

SSM Ment Health, 2023
Oluwoye O, Nagendra A, Kriegel LS, Anglin DM, Santos MM, López SR.   +5 more
europepmc   +1 more source