Results 161 to 170 of about 10,730,120 (241)
Efrain Talamantes,1 Gerardo Moreno,2 Lourdes R Guerrero,3 Carol M Mangione,3,4 Leo S Morales5,6 1US Department of Veterans Affairs and Division of General Internal Medicine, Division of General Internal Medicine and Health Services Research, University ...
Talamantes E +4 more
core
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Response to Letter to the Editor on "Development and validation of PEYRO-Q: a novel multidimensional patient-reported outcome measure for Peyronie's disease". [PDF]
Cocci A, Lo Re M.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Patient-Reported Outcome Measure of Communication Difficulties in Friedreich Ataxia: COMATAX. [PDF]
Buchholz M +32 more
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Responsiveness of the NAIL-Q Patient-Reported Outcome Measure. [PDF]
Forman CA +7 more
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Patient-reported outcome measure completion in lumbar spine surgery: Rates and determinants in a multicenter registry. [PDF]
Mocking J +4 more
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

