Results 91 to 100 of about 283,363 (263)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Comparison of Patient’s Rights in Developed Countries and Suggestion a Proper Model for Iran

open access: yesمدیریت اطلاعات سلامت, 2011
Introduction: In health care, emphasis on basic human rights is especially important. Patient’s privacy protection becomes important when the human is exposed to shortcomings of social and health systems. This study was performed to compare the patient’s
Masoumeh Sarbaz, Khalil Kimiafar
doaj  

Psychiatric Boarding in New Hampshire: Violation of a Statutory Right to Treatment [PDF]

open access: yes, 2016
[Excerpt] New Hampshire law provides for the involuntary commitment of a patient such as Jane when she is a danger to herself or others as a result of mental illness. The patient has a right to treatment under N.H. Rev. Stat. Ann.
McClure, James A.
core   +1 more source

Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal [PDF]

open access: yes, 2017
Current guidelines support the well-established clinical practice that patients who present with atrial fibrillation (AF) of less than 48 hours duration should be considered for cardioversion, even in the absence of pre-existing anticoagulation. However,
Rankin, Alastair J., Rankin, Stephen H.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The Status of Observing the Charter of Patients’ Rights and Related Factors from the Point of View of Hospitalized Patients

open access: yesJournal of Holistic Nursing and Midwifery, 2020
Introduction: Adherence to patients’ rights is one of the most important ethical issues in the hospital that should be considered. An efficient health system requires active participation and proper interaction between health care recipients and ...
Seyedeh Narjes Fazeli   +3 more
doaj  

Personalizing Situated Workflows for Pervasive Healthcare Applications [PDF]

open access: yes, 2008
In this paper, we present an approach where a workflow system is combined with a policy-based framework for the specification and enforcement of policies for healthcare applications.
Dong, Changyu   +2 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Preconception Care of Women on Prescribed Opioids [PDF]

open access: yes, 2017
The landmark 2015 report from the Center for Disease Control (CDC) posited that too many women of reproductive age received prescribed opioids. This is significant because fetal exposure to a known teratogen can have catastrophic outcomes.
Norwick, Rebecca-Maria
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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