Results 71 to 80 of about 283,363 (263)

Getting research findings into practice : when to act on the evidence. [PDF]

open access: yes, 1998
There is increasing interest in providing evidence based health care—that is, care in which healthcare professionals, provider managers, those who commission health care, the public, and policymakers consistently consider research evidence when making ...
Guyatt, G H, Haines, A, Sheldon, T A
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Perspective of patients and their relatives about the patients’ rights in the hospitals of Khoy University of Medical Sciences

open access: yesفصلنامه پرستاری،مامایی و پیراپزشکی, 2017
Background & Aim: Patient's bill of rights is one of the most important aspects of the clinical services that its observation can cause patient and staff satisfaction. Lack of it leads to complications and patient mistrust of the health care workers. The
Leila Mokhtari, Abdollah Khorami Markani
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Regulacje prawne w zakresie opieki okołoporodowej w Polsce w kontekście projektu nowego standardu organizacyjnego

open access: yesStudia Prawa Publicznego, 2018
Pursuant to Article 68(3) of the Constitution of the Republic of Poland, a pregnant woman is entitled to special care from the State. Therefore, it seems extremely important to indicate uniform, universally binding standards in order to improve the ...
Zuzanna Witek
doaj   +1 more source

Adapting clinical guidelines to take account of multimorbidity [PDF]

open access: yes, 2012
Most people with a chronic condition have multimorbidity, but clinical guidelines almost entirely focus on single conditions. It will never be possible to have good evidence for every possible combination of conditions, but guidelines could be made more ...
Alderson, P.   +4 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Prawa pacjenta z perspektywy funkcjonalnej refleksji

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2014
In 1991 was passed in Poland the Healthcare Institutions Act. In the cited act was for the first time used the phrase of „patient’s rights”. Currently in our country there are several other laws that directly relate to that issue.
Błażej Kmieciak
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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