Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Patient centered infertility care: The health care provider’s perspective
Patient Experience Journal, 2015 This study describes what health care providers (HCPs) of fertility services perceive their patients to value most, as well as HCPs’ self-evaluation in provision of patient centered infertility care (PCIC).
Alana Streisfield +3 more
doaj
Comparison of clinical characteristics and short-term outcomes among COVID-19 patients in a tertiary care center during second wave pandemic in Nepal: a cross-sectional study [PDF]
, 2022 Nabin Simkhada +9 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A comparison of buprenorphine induction strategies: Patient-centered home-based inductions versus standard-of-care office-based inductions [PDF]
, 2011 Chinazo O. Cunningham +5 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Editorial: Palliative care for people living with heart and lung disease
Frontiers in Cardiovascular Medicine, 2023 Piotr Z. Sobanski +3 more
doaj +1 more source
Patient Experience Journal, 2015 Chronic illnesses like type 2 diabetes are costly and difficult to treat. Patient-centered medical homes (PCMH) have the potential to improve patient satisfaction in this population. However, which domains have the most impact on patient satisfaction has
Jon Mills +5 more
doaj
Development and Piloting of a Patient Centered, Risk-Stratified Supportive Care Clinical Pathway for Head & Neck Cancer Patients in a Chilean Cancer Center [PDF]
, 2019 Laura González +3 more
openalex +1 more source