Results 131 to 140 of about 3,046,490 (341)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Evolution, similarities and differences between patient-centered care and person-centered care

Revista Información Científica
Introduction: in recent years, given the avalanche of technology and specialization in the health sector, the concept of medicine centered on the patient and then on the person was introduced, which emphasizes the individual care of patients as subjects,
Migdalia Fernández Villalón, Yanet del Carmen Pérez Ferreiro, Emma Aurora Bastart Ortiz, Reinaldo Reyes Mediaceja, Marlene Marina Gorguet Pi   +4 more
doaj   +1 more source

Patient Outcomes and Lessons Learned From Treating Patients With Severe COVID-19 at a Long-term Acute Care Hospital: Single-Center Retrospective Study [PDF]

, 2022
Pete Grevelding, Henry C. Hrdlicka, Steve Holland, Lorraine Cullen, Amanda Meyer, Catherine Connors, Darielle Cooper, Allison Greco   +7 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Six ways to get a grip on patient and family centered care during the undergraduate medical years

Canadian Medical Education Journal
Patient and family-centered care and patient engagement practices have strong evidence-based links with quality and safety for both patients and health care providers.
Krista Baerg, Tara Anderson, Heather Thiessen   +2 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

MON-667 Prevalence and Predictors of Diabetic Retinopathy Among Type 2 Diabetes Patients at a Tertiary Care Center

, 2020
Khaled Baagar, Fahmi Yousef Khan, Mahmoud Zirie, Sara Darwish, Ahmed Kadhim Mohammed, Aaiza Aamer, Ahmed Shady, Amr Salama, Ahmed Hussein, Hussein Adly, Wajiha Gul   +10 more
openalex   +1 more source

Integrated Electronic Health Record of Multidisciplinary Professionals Throughout the Cancer Care Pathway: A Pilot Study Exploring Patient-Centered Information in Breast Cancer Patients

, 2023
Atsuko Sugiyama, Hayato Okumiya, Katsuhiko Fujimoto, Kazuki Utsunomiya, Yuka Shimomura, Masaru Sanuki, Keitaro Kume, Takahiro Yano, Rina Kagawa, Hiroko Bando   +9 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

An experience of practitioners navigating the role of patient/caregiver

Patient Experience Journal, 2017
This journey involved one of us having (repeat) intraspinal surgery in a country far from home but of a similar culture and with the same first language. The carer travelled across the world to be present during the hospital stay.
Susan Shaw, Rain Lamdin
doaj