Results 61 to 70 of about 1,999 (160)

DNA Replication Stress‐Induced Transcriptome of Human Burkitt's Lymphoma Identifies Reciprocal Regulation Between MBD1 and BCL6 During Germinal Center‐Derived B‐Lymphomagenesis

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal, Kyoko Oichai, Hongtae Kim, Kyungjae Myung, Jacqueline H. Barlow   +4 more
wiley   +1 more source

Article Commentary: Patient-Reported Outcomes (PROs) and Patient-Reported Outcome Measures (PROMs)

Health Services Insights, 2013
In recent years, there has been an increased focus on placing patients at the center of health care research and evaluating clinical care in order to improve their experience and ensure that research is both robust and of maximum value for the use of ...
Theresa Weldring, Sheree M.S. Smith
doaj   +1 more source

Validation of novel patient-centred juvenile idiopathic arthritis-specific patient-reported outcome and experience measures (PROMs/PREMs)

Pediatric Rheumatology Online Journal, 2020
Background Measuring the outcomes that matter to children and young people (CYP) with juvenile idiopathic arthritis (JIA), is a necessary precursor to patient-centred improvements in quality of clinical care.
Laura E. Lunt, Stephanie Shoop-Worrall, Nicola Smith, Gavin Cleary, Janet McDonagh, Andrew D. Smith, Wendy Thomson, Flora McErlane   +7 more
doaj   +1 more source

SRM 1650b Administration to Isolated Rat Heart Aggravates Ischemia‐Reperfusion Injury via Mitochondrial Dysfunction and Downregulation of PI3K/Akt Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
SRM 1650b diesel particulate matter caused dose‐dependent cardiotoxicity in isolated male Wistar rat hearts, worsening hemodynamics and tissue injury after ischemia–reperfusion. It increased oxidative stress, impaired mitochondrial bioenergetics and respiration, downregulated mitochondrial quality‐control genes, reduced mtDNA copy number, and ...
Kirankumar Balu, Uvasshri Vijayakumar, Bhavana Sivakumar, Priyanka N. Prem, Gino A. Kurian   +4 more
wiley   +1 more source

Concurrent use and association of patient-reported experience and outcome measures in psychiatric and substance use disorder care: a scoping review

Frontiers in Health Services
BackgroundPatient reported experience measures (PREMs) provide patients` perspectives on health care services received, while generic Patient reported outcome measures (PROMs) reflect their subjective well-being or quality of life.
Marte Karoline Råberg Kjøllesdal, Marte Karoline Råberg Kjøllesdal, Hilde Hestad Iversen, Lina Harvold Ellingsen-Dalskau   +3 more
doaj   +1 more source

Development and validation of a patient reported experience measure for experimental cancer medicines (PREM-ECM) and their carers (PREM-ECM-Carer)

BMC Cancer
Abstract Background Our aim was to develop a validated Patient Reported Experience Measure (PREM) to capture patient and carer experience during participation in experimental cancer medicine trials (ECM): called PREM-ECM.
Sawyer, CS, Taylor, S, Carter, L, Stanworth, M, Davies, M, Thistlethwaite, F, Taylor, J, Eastwood, C, Yorke, J   +8 more
openaire   +5 more sources

Further Development and Validation of a Measure of Compassionate Healthcare in Action

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Compassionate Healthcare In Action (CHIA) is a new questionnaire to measure patient experiences of compassionate care, with a particular focus on observable behaviours. It has been designed to address gaps in currently available metrics.
Samantha R. Allen, Ellen Huish, Roxanne M. Parslow, Elizabeth Marks, Lucy A. Clarkson, Sarah Howard, Lucy Maddox   +6 more
wiley   +1 more source

The Values and Preferences of People Living With Motor Neurone Disease (MND): A Systematic Review and Meta‐Analysis

Clinical and Public Health Guidelines, Volume 3, Issue 3, July 2026.
ABSTRACT Aim To synthesise quantitative evidence on the values and preferences of people living with Motor Neurone Disease (MND), caregivers, and genetic carriers regarding health‐related outcomes to inform the Australian MND Guideline. Methods A systematic review was conducted following Cochrane and GRADE guidance, informed by an a priori protocol ...
Timothy Hugh Barker, Lemma N. Bulto, Grace Holland, Camille Schubert, Tracy Merlin, Samer G. Karam, Wojtek Wiercioch, Danielle Pollock, Cindy Stern, Jay Beasley‐Hall, Nipun Shrestha, Steve Vucic, Lynne Giles, Zachary Munn   +13 more
wiley   +1 more source

Can the jointly collection of PROMs and PREMs improve integrated care? The changing process of the assessment system for the hearth failure path in Tuscany Region

International Journal of Integrated Care, 2019
The Patient Reported Outcome and Experience Measures (PROMs and PREMs) are key assessment tools from the patients’ point of view, with different purposes and different tools.
Francesca Pennucci, Sabina De Rosis, Sabina Nuti   +2 more
doaj   +1 more source

Evaluating the Population-Based Usage and Benefit of Digitally Collected Patient-Reported Outcomes and Experiences in Patients With Chronic Diseases: The PROMchronic Study Protocol

JMIR Research Protocols
BackgroundChronic diseases are associated with a high disease burden. Under- and overprovision of care as well as quality variation between health care providers persists, while current quality indicators rarely capture the ...
Janis Nikkhah, Viktoria Steinbeck, Thomas G Grobe, Thorben Breitkreuz, Christoph Pross, Reinhard Busse   +5 more
doaj   +1 more source