Results 221 to 230 of about 2,675,009 (295)
Patient-reported outcome measurements in clinical trials in Saudi Arabia: A cross-sectional analysis of ClinicalTrials.gov. [PDF]
Al-Aqeel SA, AlKofide HA.
europepmc +1 more source
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga+8 more
wiley +1 more source
Quality of patient-reported outcome measures for acute bronchitis: a systematic review of instruments and measurement properties. [PDF]
Donhauser T+3 more
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
Development and validation of an eating behavior patient-reported outcome measure in people living with obesity or overweight. [PDF]
Bushnell DM+8 more
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SensRORing cholesterol to drive protumoral myelopoiesis
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley +1 more source