Results 231 to 240 of about 1,662,389 (298)

The Fallacy of Patient-Reported Outcome Measures: Why They Often Fail to Detect Clinically Important Differences. [PDF]

JB JS Open Access
O'Hara NN, Brodke DJ, Levack AE, O'Toole RV, Slobogean GP.   +4 more
europepmc   +1 more source

POB10 VALIDATION OF A PATIENT-REPORTED OUTCOMES QUESTIONNAIRE FOR ASSESSING POSITIVE WELL-BEING ASSOCIATED WITH BEHAVIORAL CHANGES

, 2005
X Mesrobian, Polyxane Mertzanis, S Dard
openalex   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

It's not just a questionnaire: The ins and outs of using a patient-reported outcome measure. [PDF]

Asia Pac J Oncol Nurs
Williams LA.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Correction to: Estimation of the Harvey Bradshaw Index from the Patient Reported Outcome-2 in Crohn's Disease. [PDF]

Inflamm Bowel Dis
europepmc   +1 more source

Statewide integration of electronic patient-reported outcome measures into routine oncology care: a mixed-methods implementation study. [PDF]

EClinicalMedicine
Mazariego C, Williamson K, Leon S, McCarthy K, Stuart K, Gazzard A, Arnold A, Delaney G, Girgis A, Rushton S, O'Brien T.   +10 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Discrepancies between Patient-Reported Outcomes and Clinician-Reported Outcomes in Chronic Venous Disease, Irritable Bowel Syndrome, and Peripheral Arterial Occlusive Disease

, 2006
Olivier Chassany, Philippe Le-Jeunne, Martin Duracinský, Marie-Sophie Schwalm, Marc Mathieu   +4 more
openalex   +1 more source