Results 31 to 40 of about 1,580,482 (298)

Patient-reported outcome measurement [PDF]

Journal of the Royal Society of Medicine, 2010
Alan Maynard and Karen Bloor1 raise interesting questions, particularly in relation to breast cancer. One issue is that treatment-related toxicities may not become problematic for several years, particularly when radiotherapy is administered. Research so far seems to indicate that hypofractionation causes more long-term problems than hyperfractionation,
openaire   +2 more sources

Patient-reported outcome measures [PDF]

Journal of the Royal Society of Medicine, 2007
In their recent essay (JRSM 2007;100:306-8), Maynard & Ayalew referred to the absence of patient reported outcome measures (PROM). They should have been aware that the Royal College of Surgeons of England, with the London School of Hygiene and Tropical Medicine, carried out a project to establish the feasibility of applying PROM for elective surgical ...
openaire   +3 more sources

Non–Small Cell Lung Cancer Symptom Assessment Questionnaire: Psychometric Performance and Regulatory Qualification of a Novel Patient-Reported Symptom Measure

Current Therapeutic Research, 2021
: Background: The Non–Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to incorporate the patient's perspective into evaluation of clinical benefit in advanced non–small cell lung cancer trials and meet regulatory ...
Donald M. Bushnell, MA, Thomas M. Atkinson, PhD, Kelly P. McCarrier, PhD, Astra M. Liepa, PharmD, Kendra P. DeBusk, PhD, Stephen Joel Coons, PhD   +5 more
doaj  

Response scale selection in adult pain measures: results from a literature review

Journal of Patient-Reported Outcomes, 2018
Background The purpose of this literature review was to examine the existing patient-reported outcome measurement literature to understand the empirical evidence supporting response scale selection in pain measurement for the adult population.
Shima Safikhani, Katharine S. Gries, Jeremiah J. Trudeau, David Reasner, Katja Rüdell, Stephen Joel Coons, Elizabeth Nicole Bush, Jennifer Hanlon, Lucy Abraham, Margaret Vernon   +9 more
doaj   +1 more source

Routine patient assessment and the use of patient-reported outcomes in specialized palliative care in Japan

Journal of Patient-Reported Outcomes, 2023
Background Discrepancies in symptom assessment between providers and patients are reported in cancer care, and the use of patient-reported outcome measures (PROMs) has been recommended for patients receiving palliative care.
Nao Ito, Yoko Ishii, Maho Aoyama, Hirofumi Abo, Akihiro Sakashita, Yuko Matsumura, Mitsunori Miyashita   +6 more
doaj   +1 more source

Patient reported outcomes in orthopaedics [PDF]

Journal of Orthopaedic Research, 2017
ABSTRACTPatient reported outcome measures (PROMs) are key tools when performing clinical research and PROM data are increasingly used to inform clinical decision‐making, patient‐centered care, health policy and more recently, reimbursement decisions. PROMs must possess particular properties before they are used. Thus purpose of this paper is to give an
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FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Consistent Patient-Reported Outcomes

Value in Health, 2002
Health-related quality of life (HRQL) measures extend patient outcome assessment beyond survival, adverse effects, and clinical efficacy, and reflect the patient’s perspective on the impact of disease and its treatment on functioning and wellbeing. An important objective for evaluating HRQL outcomes is to demonstrate the value of new pharmaceutical ...
openaire   +3 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source