Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
FEBS Open Bio, EarlyView.Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski +13 more
wiley +1 more source
Considerations in the selection of patient-reported outcome measures for assessing function related to chronic ankle instability. [PDF]
Front Bioeng BiotechnolLuan L +9 more
europepmc +1 more source
The effect of posterior and lateral approach on patient-reported outcome measures and physical function in patients with osteoarthritis, undergoing total hip replacement: a randomised controlled trial protocol [PDF]
, 2014 Signe Rosenlund +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Sample size used to validate a scale: a review of publications on newly-developed patient reported outcomes measures [PDF]
, 2014 Emmanuelle Anthoine +4 more
openalex +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Evaluating the measurement properties of patient-reported outcome measures for young adults with life-limiting conditions: A systematic review. [PDF]
Palliat MedChambers RL +4 more
europepmc +1 more source
Can the outcome of primary care be measured by a Patient Reported Outcome Measure? [PDF]
, 2014 Mairead Murphy +2 more
openalex +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
H-Wave device stimulation benefits chronic shoulder pain in an observational cohort study of patient-reported outcome measures. [PDF]
Sci RepNorwood SM, Han D, Gupta A.
europepmc +1 more source