Results 81 to 90 of about 23,206 (254)

A prospective natural history study protocol for clinical trial readiness in synaptic disorders

Epilepsia, EarlyView.
Abstract Objective STXBP1‐related disorder (STXBP1‐RD) and SYNGAP1‐related disorder (SYNGAP1‐RD) are two common genetic synaptopathies that are associated with epilepsy, developmental delay, intellectual developmental disorder, and behavioral problems.
Jillian L. McKee, Sarah M. Ruggiero, Kristin Cunningham, JoeyLynn Coyne, Ian McSalley, Michael C. Kaufman, Bintou Bane, Torrey Chisari, Jonathan Toib, Carlyn Glatts, Sarah Tefft, Julie M. Orlando, Viveknarayanan Padmanabhan, Alexander K. Gonzalez, Alicia Harrison, Charlene Woo, Stephanie A. Zbikowski, Rency Dhaduk, Johanna Mercurio, Macie McCarthy, Jan H. Magielski, Zachary Grinspan, Megan Abbott, Juliet Knowles, Hsiao‐Tuan Chao, Katherine Xiong, Elizabeth Berry‐Kravis, Sepideh Tabarestani, J. Michael Graglia, Kathryn Helde, Virginie McNamar, Charlene Son Rigby, James Goss, Scott Demarest, Andrea Miele, Benjamin Prosser, Michael J. Boland, Samuel R. Pierce, Ingo Helbig   +38 more
wiley   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review

Knee Surgery & Related Research
Background The present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) of several frequent and established PROMs used to assess patients ...
Filippo Migliorini, Nicola Maffulli, Luise Schäfer, Francesco Simeone, Andreas Bell, Ulf Krister Hofmann   +5 more
doaj   +1 more source

Transition From Child to Adult Eating Disorder Services: A Qualitative Meta‐Aggregation

European Eating Disorders Review, EarlyView.
ABSTRACT Background Some young people with eating disorders (EDs) require transfer from paediatric to adult services, which can be difficult and distressing. While most research on this topic is qualitative, no qualitative focused synthesis yet exists.
Amelia Austin, Manya Singh, Sela Scott, Maria Nicula, Andrea Krishnapillai, Jayden Lee, Cheryl Webb, Ana Cláudia Vieira de Almeida, Mehar Sesan, Heidi Vander Steen, Julia Hews‐Girard, Christopher J. Mushquash, Melissa Kimber, Jennifer Couturier, Gina Dimitropoulos   +14 more
wiley   +1 more source

Patient-Reported Outcome Measures (PROMs) to Support Adherence to Falls Prevention Clinic Recommendations: A Qualitative Study

Patient Preference and Adherence, 2020
Daria Tai,1– 4 Eric Li,1 Teresa Liu-Ambrose,2– 4 Nick Bansback,5,6 Mohsen Sadatsafavi,7,8 Jennifer C Davis1– 3 1Social & Economic Change Laboratory, Faculty of Management, University of British Columbia – Okanagan, Kelowna ...
Tai D, Li E, Liu-Ambrose T, Bansback N, Sadatsafavi M, Davis JC   +5 more
doaj  

Case‐Mix Adjustment of Multidimensional Patient‐Reported Outcomes to Assess Hospital Performance

Health Economics, EarlyView.
ABSTRACT Multidimensional patient‐reported outcome measures (PROMs) are increasingly used to compare the performance of health care providers. Meaningful comparisons require the data to be adjusted for differences in case‐mix. The common approach in the literature is to aggregate PROM data into univariate summary scores prior to case‐mix adjustment. In
Nils Gutacker, Yuanyuan Gu
wiley   +1 more source

Waiting Time Prioritisation for Public and Private Providers: Evidence From Hip Replacement Surgery

Health Economics, EarlyView.
ABSTRACT Waiting times for planned health care treatments have been increasing in England and other OECD countries. One policy to reduce the impact of waiting times on patients' health is for doctors to prioritise patients according to their health status. This study tests the extent to which publicly‐funded patients in poorer health are prioritised on
Panos Kasteridis, Luigi Siciliani, Peter Sivey   +2 more
wiley   +1 more source

Patient-reported outcome and experience measures in primary care: a scoping review of systematic collection and use

BMC Health Services Research
Background Patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) are increasingly recognised as essential instruments for improving quality of care, accountability, and person-centredness.
Candan Kendir, Angel Gonzalez de la Fuente, Dionne Kringos, Michael van den Berg, Jose Maria Valderas, Niek Klazinga   +5 more
doaj   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Reporting of patient-reported outcomes (PROs) in randomized controlled trials of anemia treatments for people with CKD: a scoping review

Journal of Patient-Reported Outcomes
Background Patient-reported outcomes (PROs) are key outcomes of importance for people with chronic kidney disease (CKD), and may be of even higher relevance for patients with concomitant anemia which can often be symptomatic.
Dipal M. Patel, Renee F. Wilson, Troy Gharibani, Lisa M. Wilson, Xuhao Yang, Yuanxi Jia, Karen A. Robinson   +6 more
doaj   +1 more source