Results 111 to 120 of about 6,836,441 (345)

On-line Medical Command and Patient-Initiated Refusals of Prehospital Care: Patient Outcome and Ambulance Call Report Documentation [PDF]

, 1993
David C. Cone, D.T Kim, S.J. Davidson
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Response scale selection in adult pain measures: results from a literature review

Journal of Patient-Reported Outcomes, 2018
Background The purpose of this literature review was to examine the existing patient-reported outcome measurement literature to understand the empirical evidence supporting response scale selection in pain measurement for the adult population.
Shima Safikhani, Katharine S. Gries, Jeremiah J. Trudeau, David Reasner, Katja Rüdell, Stephen Joel Coons, Elizabeth Nicole Bush, Jennifer Hanlon, Lucy Abraham, Margaret Vernon   +9 more
doaj   +1 more source

Differences in patient-reported processes and outcomes between men and women with myocardial infarction [PDF]

, 2000
Kenneth E. Covinsky, Mary‐Margaret Chren, Dwain L. Harper, Lynne E. Way, Gary E. Rosenthal   +4 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Pregnancy outcome in a patient with chronic malnutrition: Case report [PDF]

, 2000
Michael P. O’Connell, Oriole Wilson, E. A. Masson, Stephen W. Lindow   +3 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Expert consensus on implementing patient-reported outcomes in telehealth: findings from an international Delphi study

Journal of Patient-Reported Outcomes
Background Using Patient Reported Outcomes (PROs) in clinical care can reduce healthcare service utilization by improving the quality of care. Telehealth, defined by WHO, as the use of “telecommunications and virtual technology to deliver healthcare ...
Elizabeth J. Unni, Liv Marit Valen Schougaard, Olalekan Lee Aiyegbusi, Kedar K. V. Mate, Elizabeth J. Austin, Klara Greffin, Natasha Roberts, Birgith Engelst Grove, Holger Muehlan, ISOQOL Clinical practice SIG PROs in Telehealth Working Group   +9 more
doaj   +1 more source

Is the Use of Crinone for Support of the Luteal Phase Detrimental to Pregnancy Outcome After Transfer of Non-Cryopreserved Embryos in Good Prognosis Patients? A Preliminary Report [PDF]

, 2000
Christos Coutifaris, Pasquale Patrizio, Deborah J. Schafer, S. Bunso, J. Bucci, Kurt T. Barnhart   +5 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source