Results 111 to 120 of about 7,712,957 (388)

Enhancing representativeness of patient-reported outcomes in routine radiation oncology care: a quality improvement protocol to address non-response

BMJ Open
Introduction Non-response significantly undermines the representativeness of patient-reported outcome (PRO) data, thereby compromising its utility for facilitating high-value, equitable, patient-centred care in cancer clinics. Quality improvement studies
Andrea L Pusic, Jason B Liu, Chengbo Zeng, Neil E Martin, Maria O Edelen   +4 more
doaj   +1 more source

Comorbidities in Patients with Rheumatoid Arthritis and Their Association with Patient-reported Outcomes: Results of Claims Data Linked to Questionnaire Survey

Journal of Rheumatology, 2019
Objective. To investigate the prevalence of comorbidities in a population-based cohort of persons with rheumatoid arthritis (RA) compared to matched controls and to examine their association with patient-reported outcomes in a survey sample.
A. Luque Ramos, I. Redeker, F. Hoffmann, J. Callhoff, A. Zink, K. Albrecht   +5 more
semanticscholar   +1 more source

Are TKA kinematics during closed kinetic chain exercises associated with patient-reported outcomes? A preliminary analysis [PDF]

, 2020
BackgroundKinematic patterns after TKA can vary considerably from those of the native knee. It is unknown, however, if there is a relationship between a given kinematic pattern and patient satisfaction after TKA.Questions/purposesIs there an association ...
Van Der Straeten, Catherine, Van Eenoo, Wies, Van Onsem, Stefaan, Verstraete, Matthias, Victor, Jan   +4 more
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Non–Small Cell Lung Cancer Symptom Assessment Questionnaire: Psychometric Performance and Regulatory Qualification of a Novel Patient-Reported Symptom Measure

Current Therapeutic Research, 2021
: Background: The Non–Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to incorporate the patient's perspective into evaluation of clinical benefit in advanced non–small cell lung cancer trials and meet regulatory ...
Donald M. Bushnell, MA, Thomas M. Atkinson, PhD, Kelly P. McCarrier, PhD, Astra M. Liepa, PharmD, Kendra P. DeBusk, PhD, Stephen Joel Coons, PhD   +5 more
doaj  

Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study. [PDF]

, 2019
OBJECTIVE: To determine the effect of erenumab, a human monoclonal antibody targeting the calcitonin gene-related peptide receptor, on health-related quality of life (HRQoL), headache impact, and disability in patients with chronic migraine (CM). METHODS:
Cheng, Sunfa, Desai, Pooja, Lenz, Robert, Leonardi, Dean K., Lipton, Richard B., Mikol, Daniel D., Nilsen, Jon, Reuter, Uwe, Silberstein, Stephen, Stewart, Walter F., Tepper, Stewart J.   +10 more
core   +1 more source

How could patient reported outcomes improve patient management in chronic myeloid leukemia? [PDF]

, 2017
Introduction: Patients reported outcome (PRO) are still under-used in patients with chronic myeloid leukemia (CML) treated with tyrosine kinase inhibitors (TKIs), though data on the correlation between quality of life (QoL) and therapeutic efficacy are ...
De Marchi, F, Fanin, Renato, Medeot, M, Tiribelli, Mario   +3 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Perfect health not so perfect after all – a methodological study on patient-reported outcome measures in 2574 patients following percutaneous coronary intervention

Health and Quality of Life Outcomes
Background Patient-reported outcome measures (PROMs) are crucial to capture patients’ health and illness status. Selecting the most suitable PROM to measure self-reported health in a specific study population is essential.
T. M. Norekvål, M. M. Iversen, K. Oterhals, H. Allore, B. Borregaard, T. R. Pettersen, D. R. Thompson, A. D. Zwisler, K. Breivik   +8 more
doaj   +1 more source