Predicting patient-reported outcomes of radiofrequency uvulopalatoplasty with tonsillectomy in adult obstructive sleep apnea. [PDF]
Tschopp S+5 more
europepmc +1 more source
Symptom Monitoring in Pediatric Oncology Using Patient-Reported Outcomes: Why, How, and Where Next
A. Leahy, C. Feudtner, E. Basch
semanticscholar +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Patient Reported Outcomes in Primary Sclerosing Cholangitis: An Australian Perspective. [PDF]
Tan N+15 more
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Systematic evaluation of patient-reported outcomes in clinical trials of digital health in cardiovascular diseases. [PDF]
Wang Q+8 more
europepmc +1 more source
PPN9 AGREEMENT BETWEEN PATIENTS' AND CLINICIANS'- REPORTED OUTCOMES IN 3 CHRONIC DISEASES
O Chassany, P. Le Jeunne
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source