Results 291 to 300 of about 8,093,285 (389)

Adalimumab improves joint-related and skin-related functional impairment in patients with psoriatic arthritis: patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial [PDF]

, 2006
Dafna D. Gladman, Philip J. Mease, M. Cifaldi, Renee Perdok, Eric H. Sasso, J Medich   +5 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aesthetics and Patient-Reported Outcomes in Periodontology and Implant Dentistry: Consensus Report. [PDF]

J Clin Periodontol
Tonetti M, Sanz M, Cairo F, Nart J, Chapple I, Aimetti M, Aroca S, Avila-Ortiz G, Blanco J, Bujaldón A, Cavalcanti R, Cortellini P, Cosyn J, Danser M, de Sanctis M, Derks J, Dommisch H, Figuero E, Gianserra R, Graziani F, Jepsen S, Kebschull M, Lambert F, Montero E, Naenni N, Needleman I, Pilloni A, Ramanauskaite A, Roccuzzo M, Sanz-Martín I, Sanz-Sánchez I, Schwarz F, Sculean A, Stefanini M, Thoma D, Trombelli L, Valles C, West N, Zucchelli G, Zuhr O, Herrera D.   +40 more
europepmc   +1 more source

Effect of patient characteristics on reported outcomes after total knee replacement [PDF]

, 2006
Antonio Escobar, José M. Quintana, Amaia Bilbao, Jesús Azkárate, José Ignacio Güenaga, Juan Carlos Arenaza, Luis‐Felipe Gutiérrez   +6 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Patient-Reported Outcomes in Older Adults With Transthyretin Amyloid Cardiomyopathy: When the Heart Isn't the Only Matter. [PDF]

JACC Adv
Zeis T, Chen V, Tang WHW, Goyal P, Hanna M, Damluji A, Martyn T.   +6 more
europepmc   +1 more source

Longitudinal deteriorations in patient reported outcomes in patients with COPD [PDF]

, 2006
Toru Oga, Koichi Nishimura, Mitsuhiro Tsukino, Susumu Satō, Takashi Hajiro, Michiaki Mishima   +5 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Early Patient-Reported Outcomes as Predictors of Long-Term Scar Satisfaction: An Exploratory Cohort Study. [PDF]

Wound Repair Regen
Nguyen A, Li R, Galiano R.
europepmc   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source