Results 51 to 60 of about 85,512 (248)

Reduction of patient specific quality assurance through plan complexity metrics for VMAT plans with an open-source TPS script

Zeitschrift für Medizinische Physik
Purpose: Volumetric modulated arc therapy (VMAT) is a widespread technique for the delivery of normo-fractionated radiation therapy (NFRT) and stereotactic body radiation therapy (SBRT).
Klara Uher, Stefanie Ehrbar, Stephanie Tanadini-Lang, Riccardo Dal Bello   +3 more
doaj   +1 more source

Patient-Specific Quality Assurance Using a 3D-Printed Chest Phantom for Intraoperative Radiotherapy in Breast Cancer

Frontiers in Oncology, 2021
This study aims to confirm the usefulness of patient-specific quality assurance (PSQA) using three-dimensional (3D)-printed phantoms in ensuring the stability of IORT and the precision of the treatment administered.
Yeonho Choi, Ik Jae Lee, Kwangwoo Park, Kyung Ran Park, Yeona Cho, Jun Won Kim, Ho Lee   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Patient-Specific quality assurance protocol for volumetric modulated arc therapy using dose volume histogram

Journal of Medical Physics, 2018
A retrospective study was performed to explore the use of dose volume histogram (DVH) metrics in a patient-specific quality assurance protocol for volumetric modulated arc therapy (VMAT).
Christopher Low, Warren Toye, Peter Phung, Christopher Huston   +3 more
doaj   +1 more source

Pretreatment patient-specific quality assurance prediction based on 1D complexity metrics and 3D planning dose: classification, gamma passing rates, and DVH metrics

Radiation Oncology, 2023
Purpose Highly modulated radiotherapy plans aim to achieve target conformality and spare organs at risk, but the high complexity of the plan may increase the uncertainty of treatment.
Liyuan Chen, Huanli Luo, Shi Li, Xia Tan, Bin Feng, Xin Yang, Ying Wang, Fu Jin   +7 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Evaluation of 2D ion chamber arrays for patient specific quality assurance using a static phantom at a 0.35 T MR-Linac

Zeitschrift für Medizinische Physik
Introduction: Patient specific quality assurance (QA) in MR-Linacs can be performed with MR-compatible ion chamber arrays. However, the presence of a static magnetic field can alter the angular response of such arrays substantially.
C. Katharina Renkamp, Daniela Eulenstein, Moritz Sebald, Fabian Schlüter, Carolin Buchele, Carolin Rippke, Jürgen P. Debus, Sebastian Klüter   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Impact of log file source and data frequency on accuracy of log file-based patient specific quality assurance

Zeitschrift für Medizinische Physik
Performing phantom measurements for patient-specific quality assurance (PSQA) adds a significant amount of time to the adaptive radiotherapy procedure. Log file based PSQA can be used to increase the efficiency of this process.
Akbar Azzi, Gerd Heilemann, Dietmar Georg, Supriyanto Ardjo Pawiro, Terry Mart, Wolfgang Lechner   +5 more
doaj   +1 more source

Prediction models as decision-support tools for virtual patient-specific quality assurance of helical tomotherapy plans

Physics and Imaging in Radiation Oncology, 2023
Background and purpose: Prediction models may be reliable decision-support tools to reduce the workload associated with the measurement-based patient-specific quality assurance (PSQA) of radiotherapy plans.
Samuele Cavinato, Andrea Bettinelli, Francesca Dusi, Marco Fusella, Alessandra Germani, Francesca Marturano, Marta Paiusco, Nicola Pivato, Marco Andrea Rossato, Alessandro Scaggion   +9 more
doaj   +1 more source