Results 121 to 130 of about 682,410 (313)

Treatment seeking behavior and related factors in patients with acute coronary syndrome

Journal of Holistic Nursing and Midwifery, 2016
Introduction: Acute Coronary syndrome is one of the most diagnosed and causes of death in the world, and treatment seeking behavior at the time of onset of symptoms and time spend on arriving to hospital is important for these patients, as it effects ...
Tahere Taghizadeh-valdi, Seyedeh Noshaz T1, Mirhaghjou, Mohammad Taghi .N2*, Moghadamnia, Ehs , Kazemnezhad Leili   +3 more
doaj  

Trends in palliative care utilization among older adult decedents with and without cancer in Taiwan: a population-based comparative studyResearch in context

The Lancet Regional Health. Western Pacific
Summary: Background: The leading causes of death among the older adults have shifted from cancer to non-cancer conditions such as ischemia heart diseases, stroke, and dementia, affecting end-of-life care needs.
Yu-Tai Lo, Tzu-Jung Chuang, Yu-Tung Huang, Yi-Lin Wu, Yi-Ching Yang, Chung-Yi Li   +5 more
doaj   +1 more source

Determinants and underlying causes of frequent attendance in midwife-led care: an exploratory cross-sectional study

BMC Pregnancy and Childbirth, 2019
Background An adequate number of prenatal consultations is beneficial to the health of the mother and fetus. Guidelines recommend an average of 5–14 consultations.
Janneke T. Gitsels – van der Wal, Lisanne A. Gitsels, Angelo Hooker, Britte van Weert, Linda Martin, Esther I. Feijen – de Jong   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Women’s experiences of wearing therapeutic footwear in three European countries [PDF]

, 2010
Background: Therapeutic footwear is recommended for those people with severe foot problems associated with rheumatoid arthritis (RA). However, it is known that many do not wear them.
A Williams, AE Williams, AE Williams, Anita E Williams, Anke Kottink, ARMA (Arthritis and Musculoskeletal Alliance), C Park, Christopher J Nester, Commission Audit, D Whalley, Disabled Living Foundation, FC Arnett, GJ Treharne, HG Gadamer, J Attride-Stirling, J Horder, J Stewart, JJ van Netten, K Aspegren, L Grondal, LML Ong, M Easley, M Fransen, M Janninck, Michael I Ravey, Morey-Gaspar Klapsing, NICE (National Institute for Clinical Excellence), P Bowker, RL Street, S Gutweniger, S Mulhall, S Ryan, SJ Otter, T Koch, V Cooper   +34 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

AAPM medical physics practice guideline 10.a.: Scope of practice for clinical medical physics. [PDF]

, 2018
The American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and professional practice of medical physics.
Anthony Seibert, J, Baird, Christopher T, Clements, Jessica B, de Boer, Steven F, Fairobent, Lynne A, Fisher, Tyler, Goodwin, James H, Gress, Dustin A, Johnson, Jennifer Lynn, Kolsky, Kathryn L, Mageras, Gig S, Marsh, Rebecca M, Martin, Melissa C, Parker, Brent, Pavord, Daniel C, Schell, Michael C, Stevens, Donna M, Tarver, Russell B, Waite-Jones, Christopher G, Wingreen, Nicholai   +19 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The disappearance of the "revolving door" patient in Scottish general practice: successful policies [PDF]

, 2012
<b>Background</b> We describe the health of "revolving door" patients in general practice in Scotland, estimate changes in their number over the timescale of the study, and explore reasons for changes, particularly related to NHS and ...
Andrea E Williamson, B Charlin, CA O'Donnell, D O'Reilly, J Greene, J Munro, JCM Gillies, JL Geller, K Charmaz, Kenneth Mullen, Paul CD Johnson, Philip Wilson, RR Donnelley   +12 more
core   +4 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source