Results 121 to 130 of about 687,161 (310)
Background An adequate number of prenatal consultations is beneficial to the health of the mother and fetus. Guidelines recommend an average of 5–14 consultations.
Janneke T. Gitsels – van der Wal +5 more
doaj +1 more source
Abstract Purpose Physical activity is a key component of cardiac rehabilitation (CR). Despite the widely reported benefits of CR, uptake in the United Kingdom is still low. Alternative home-based and technology-facilitated delivery models are needed to improve CR uptake and physical activity.
Daniella Springett +6 more
openaire +2 more sources
Background. Clinical teaching is central in the training of medical students. Although medical studies without practice are hard to imagine nowadays, for most patients this type of learning is still difficult to understand and not always acceptable. Materials and methods. A prospective anonymous survey of 150 participants was carried out.
Kasparas Rubliauskas +2 more
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Is moderate hypofractionation accepted as a new standard of care in north america for prostate cancer patients treated with external beam radiotherapy? Survey of genitourinary expert radiation oncologists [PDF]
INTRODUCTION: Several recent randomized clinical trials have evaluated hypofractionated regimens against conventionally fractionated EBRT and shown similar effectiveness with conflicting toxicity results.
Chen, Yiyi +5 more
core +2 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
spotlight no. 5, 2018 - #SmartHealthSystems Digitalization requires an effective strategy, compelling political leadership and a coordinating institution with a national mandate [PDF]
In terms of digitalizing its healthcare sector, Germany trails far behind several other countries as the potential for quality and efficiency in German healthcare remains untapped ●● Countries that are succeeding in digitalizing their healthcare systems ...
Kostera, Thomas, Thranberend, Timo
core

