Results 51 to 60 of about 169,466,874 (244)

‘I’ve put diabetes completely on the shelf till the mental stuff is in place’. How patients with doctor-assessed impaired self-care perceive disease, self-care, and support from general practitioners. A qualitative study

open access: yesScandinavian Journal of Primary Health Care, 2018
Objective: This paper investigated patients’ experiences of disease and self-care as well as perceptions of the general practitioner’s role in supporting patients with impaired self-care ability.
Mads Aage Toft Kristensen   +4 more
doaj   +1 more source

The effect of a terrorist attack on emergency department inflow: an observation study using difference-in-differences methodology

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Study objective The objective of this study was to investigate how the terrorist attack in Stockholm, Sweden affected patient inflow to the general emergency departments (EDs) in close proximity of the attack.
Andreas Ekström   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Factors associated with preconception care behaviors and behavioral stages among emerging adults: a cross-sectional study

open access: yesFrontiers in Public Health
BackgroundIt remains a challenge to promote reproductive healthcare behaviors—including preconception care—among emerging adults. To effectively influence behavioral changes among emerging adults, it is necessary to understand their behavior according to
Inhae Cho, Hyunjeong Shin, Songi Jeon
doaj   +1 more source

Acceptability and adoption of clinical practice guidelines and treatment protocols on preeclampsia/eclampsia in the Dominican Republic

open access: yesRevista Panamericana de Salud Pública, 2021
Objective. Estimate the acceptability and adoption by health care workers of clinical practice guidelines and treatment protocols for women with preeclampsia/eclampsia and identify the facilitating factors and barriers to their implementation. Methods. A
Andelys De la Rosa   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A mixed-method service evaluation of health information exchange in England: technology acceptance and barriers and facilitators to adoption

open access: yesBMC Health Services Research, 2021
Background The need for information exchange and integrated care has stimulated the development of interoperability solutions that bring together patient data across the health and care system to enable effective information sharing.
Fiona Watkinson   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Patient Centred Assessment Method (PCAM) : integrating the social dimensions of health into primary care [PDF]

open access: yes, 2015
Acknowledgments We wish to acknowledge Maracan Baird and C.J. Peek at the Department of Family Medicine and Community Health, University of Minnesota, for allowing the MCAM tool to be further developed, and for working in partnership with the research ...
Cameron, Isobel   +8 more
core   +1 more source

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