Results 221 to 230 of about 5,399,581 (311)

Expert consensus on patient engagement strategies for improving patient activation and shared decision making in pulmonary arterial hypertension. [PDF]

J Am Assoc Nurse Pract
Ryan JJ, Wilson M, Saggar R, Benninger C, Bridge D, Cho M, Doad G, Enstone A, Han M, Perrett L, Perry R, Smith H, Stone M, Lombardi S.   +13 more
europepmc   +1 more source

Sexual activity and the post coronary patient

Journal of Rehabilitation Medicine, 1970
H K, Hellerstein, E H, Friedman
openaire   +3 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Patient Activation and Diabetes Outcomes Among Jordanian Patients With Type 2 Diabetes: Longitudinal Evidence on Adherence and Glycemic Control With Linear Mixed Model Analysis. [PDF]

Res Nurs Health
Alosta MR, Atiyeh H, Hani SB, Hamdan-Mansour A, Al-Yyan AA, Afaneh T, Sarhan R, Al-Momani M, Othman EH.   +8 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Relationship between patient activation, experienced stigma, and internalised weight stigma in people with type 2 diabetes. [PDF]

Diabet Med
Sims TJ, Kapoor R, Chinthammit C, Spaepen E.   +3 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Patient activation levels in cardiovascular disease: a cross-sectional study in Brazilian community pharmacies. [PDF]

Sao Paulo Med J
Iglecias FM, Riano E, Ferreira-Alfaya FJ, Valverde-Merino MI, Gomez-Guzman M, Piquer-Martinez C, Zarzuelo MJ.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sleep Quality and Patient Activation in Chronic Disease: A Cross-Sectional Mediation Analysis. [PDF]

Clocks Sleep
Wiedermann CJ, Barbieri V, Lombardo S, Gärtner T, Eisendle K, Piccoliori G, Engl A, Ausserhofer D.   +7 more
europepmc   +1 more source