Results 141 to 150 of about 1,300,784 (306)

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Risk factors for in-patient admission among adults with intellectual disability and autism: investigation of electronic clinical records. [PDF]

BJPsych Open, 2020
Sheehan R, Mutch J, Marston L, Osborn D, Hassiotis A.   +4 more
europepmc   +1 more source

The Patient-Physician Relationship: Overcoming Language and Cultural Barriers [PDF]

, 2019
The patient-physician relationship governs the field of medicine, forming the basis for all relationships, interactions, and procedures in medicine. The degree to which a patient trusts his physician and thus is willing to be receptive to medical advice ...
Lynch, Corrilynn
core   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Hora da admissão na unidade de emergência e mortalidade hospitalar na síndrome coronária aguda Emergency service admission time and in-hospital mortality in acute coronary syndrome

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: Há controvérsias sobre a hora da admissão e os desfechos hospitalares da síndrome coronária aguda (SCA). A admissão em horários não regulares seria associada ao pior prognóstico dos pacientes.
Julio Yoshio Takada, Larissa Cardoso Roza, Rogério Bicudo Ramos, Solange Desiree Avakian, José Antonio Franchini Ramires, Antonio de Pádua Mansur   +5 more
doaj  

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Streamlining patient flow and enhancing operational efficiency through case management implementation

BMJ Open Quality
Background Improving patient flow in hospitals represents a worldwide healthcare challenge. The objective of this project was to depict the effectiveness of case management in improving patient flow in a tertiary hospital setting.Methods Quality ...
Sultanah Al Harbi, Baker Aljohani, Lamiaa Elmasry, Frenk Lee Baldovino, Kamille Bianca Raviz, Lama Altowairqi, Seetah Alshlowi   +6 more
doaj   +1 more source

Estimating hospital catchments from in-patient admission records: a spatial statistical approach applied to malaria. [PDF]

Sci Rep, 2020
Alegana VA, Khazenzi C, Akech SO, Snow RW.   +3 more
europepmc   +1 more source