Results 111 to 120 of about 19,606 (268)

Systematic review on the frequency and quality of reporting patient and public involvement in patient safety research

BMC Health Services Research
Background In recent years, patient and public involvement (PPI) in research has significantly increased; however, the reporting of PPI remains poor. The Guidance for Reporting Involvement of Patients and the Public (GRIPP2) was developed to enhance the ...
Sahar Hammoud, Laith Alsabek, Lisa Rogers, Eilish McAuliffe   +3 more
doaj   +1 more source

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source

Researchers' Perspectives and Guidelines on the Reporting of Lived Experience Involvement in Eating Disorder Research

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objectives There is an increasing trend towards embedding consumer and community involvement in all health and medical research. The Executive Committee of the International Journal of Eating Disorders (IJED) disseminated a survey for eating disorder researchers investigating their practices and perspectives regarding Patient and Public ...
Tracey D. Wade, Marcela Radunz, Jake Linardon, Scott J. Crow, Ata Ghaderi, Anja Hilbert, Kelly L. Klump, B. Timothy Walsh, Ruth Weissman   +8 more
wiley   +1 more source

Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 761-769, April 2025.
Abstract Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day‐care units; the safety and effectiveness of outpatient‐based management (OPM) for ADHF has not been established.
Jameela Bahar, Amna Rahman, Grace W.Y. Wong, Rajiv Sankaranarayanan, Fozia Z. Ahmed, Rebecca Taylor, Ahmet Fuat, Iain Squire, John G.F. Cleland, Gregory Y.H. Lip, James H.P. Gamble, Sundas Masudi, Prince Josiah S. Joseph, Kenneth Y.K. Wong   +13 more
wiley   +1 more source

Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy

Epilepsia, EarlyView.
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber, Tristan Manfred Stöber, Vanessa Schütz, Lara Costard, Valentin Neubert, Sebastian Bauer, Parsa Gharavi, Julika Pitsch, Nico Melzer, Adam Strzelczyk, Jochen Triesch, Kai Siebenbrodt, Felix Rosenow, Ricardo Kienitz   +13 more
wiley   +1 more source

‘We Need Help Too’—The Forgotten Stakeholders: Exploring the Needs of Carers During Their Young Persons' Transition From Child to Adult Eating Disorder Services

European Eating Disorders Review, EarlyView.
ABSTRACT Background Carers are essential in their young person's recovery during transition from child to adult eating disorder services. Despite recommendations, carer's own needs can be overlooked in transition planning. Subsequently, carers experience distress in supporting their young person and navigating the transition.
Isabel Lenham, Maria Livanou, Anya Heneghan, Grace Hill, Alanta McKenzie, Marta Marlais, Francesca Marshall, Zara Smalley, Eleni Xanthopoulou, Nora Kornai, Jessica Wilks, Ailsa McKay, Jun Teh, Julian Baudinet   +13 more
wiley   +1 more source

Identifying challenges and enablers to engaging patients in preclinical laboratory research: an interview study

Research Involvement and Engagement
Background Patient engagement in research enriches study design, conduct, and dissemination by integrating lived experiences of patients into the research process.
Madison Foster, Dean A. Fergusson, Emily Thompson, Victoria Hunniford, Talston Scott, Stephen Daniels, Dawn P. Richards, Pat Messner, Kathryn Hendrick, Patrick Sullivan, Asher A. Mendelson, Kimberly F. Macala, Kirsten M. Fiest, Angela M. Crawley, Bernard Thébaud, Stuart G. Nicholls, Cheryle A. Séguin, Grace Fox, Justin Presseau, Manoj M. Lalu   +19 more
doaj   +1 more source

Patients’ and researchers’ experiences with a patient board for a clinical trial on urinary tract infections

Research Involvement and Engagement, 2019
Background Patient and public involvement (PPI) has become an essential part of the design, conduct, and dissemination of research. While researchers who employed PPI mainly report on the positive aspects, in practice PPI is still an exception in ...
Imke Schilling, Heike Behrens, Jutta Bleidorn, Ildikó Gágyor, Claudia Hugenschmidt, Hannah Jilani, Guido Schmiemann, Ansgar Gerhardus   +7 more
doaj   +1 more source

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

What Can Providers' Motivations Tell Us About Healthcare Quality?

Health Economics, EarlyView.
ABSTRACT Agency theory suggests that variation in providers' quality of care may be explained by their heterogeneous motivations. We provide novel empirical evidence on the links between different sources of provider motivation and quality of care by combining a unique 4‐year survey dataset on Danish general practitioners' motivations with quality ...
Lucy Margaret Poole, Line Bjørnskov Pedersen, Anne Sophie Oxholm   +2 more
wiley   +1 more source