Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Intuition in Healthcare Communication Practices: Initial Findings from a Qualitative Inquiry [PDF]
, 2017 This brief paper reports on how healthcare providers negotiate stages of care and communication by using intuition. This focus shifts attention away from the product-patient records-and towards the process of medical communication. To support this claim,
Angeli, Elizabeth L., Campbell, Lillian
core +1 more source
Carcinoma of the cervix in elderly patients treated with radiotherapy: patterns of care and treatment outcomes [PDF]
, 2016 Ming Yin Lin +4 more
openalex +1 more source
Factors related to post-traumatic stress disorder among nurses after directly caring for patients with COVID-19: a cross-sectional study [PDF]
, 2023 Hyo‐Jeong Yoon +2 more
openalex +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
RWD68 Early Optimal Recovery As a Composite Outcome to Measure Value of Care in Patients Undergoing Primary Total Knee Arthroplasty with a New Implant Design [PDF]
, 2023 van Keulen L +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Promoting patient‐centered‐care through a virtual reality medical school curriculum focused on dementia and end‐of‐life in the COVID Era [PDF]
, 2023 Olivia Negris +7 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source