Results 231 to 240 of about 5,583,734 (354)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Readmissions to a Surgical Intensive Care Unit: Incidence and Risk Stratification for Personalized Patient Care. [PDF]

J Pers Med
Ramos S, Ramos Fernández R, Sevilla R, Cabezuelo E, Calvo A, Vela R, Menendez C, Garcia Ramos S, Hortal Iglesias J, Garutti I, Piñeiro P.   +10 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correction: Enhancing nursing documentation in Kazakhstan: assessing utilization and standardization for improving patient care. [PDF]

Front Public Health
Sydykova B, Smailova D, Khismetova Z, Brimzhanova M, Baigozhina Z, Hosseini H, Latypova N, Izmailovich M.   +7 more
europepmc   +1 more source

Patient care [PDF]

Bone Marrow Transplantation, 2001
openaire   +1 more source

A Clinical and Analytical Study of Surgical and Patient-Centered Outcomes of Open Haemorrhoidectomy and Chivate's Procedure at a Tertiary Care Centre in Central India [PDF]

Ashok Kalbi, Ganesh Kharkate, Raj Gajbhiye   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Systematic Review of Smartphone Applications That Address Patient Care in the Peri-Operative Period. [PDF]

Healthcare (Basel)
El-Hadi H, Chan BL, Siu BW, Ko IC, Leung DK, Teoh JY, Chiu PK, Ng CF, Liu AQ.   +8 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source