Results 201 to 210 of about 1,434,335 (357)

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

Advanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu   +11 more
wiley   +1 more source

Advancing the Care Experience for Patients Receiving Palliative Care as They Transition From Hospital to Home (ACEPATH): Phase 2 of Codesigning an Intervention to Improve Hospital-to-Home Transitions for Patients and Family Caregivers. [PDF]

Health Expect
McCoy M, Shorting T, Mysore VK, Fitzgibbon E, Rice J, Savigny M, Ernecoff NC, Weiss M, Bush SH, Vincent D, Hagarty M, Lalumière G, Pattison R, Kornberg M, Stern M, Kuluski K, Webber C, Bruni A, Connolly T, Isenberg SR.   +19 more
europepmc   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

There is no 'one size fits all' model of care for patients with behavioural and psychological symptoms of dementia in hospital. [PDF]

Australas J Ageing
Graham FA, Gordon EH.
europepmc   +1 more source

Measuring Social Network Structure of Clinical Teams Caring for Patients with Complex Conditions

, 2011
Margaret Palazzolo, Francesca Grippa, Andrea Booth, Stacy Rechner, John C. Bucuvalas, Peter A. Gloor   +5 more
openalex   +1 more source

Implementation challenges in delivering team-based care (‘TEAMcare’) for patients with chronic obstructive pulmonary disease in a public hospital setting: a mixed methods approach [PDF]

, 2016
Belinda Cochrane, Jann Foster, Robert D. Boyd, Evan Atlantis   +3 more
openalex   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Empowering orthopedic nurses' and nurse's aides through a multimodal geriatric mobile team: a mixed methods study. [PDF]

BMC Nurs
Genet B, Cohen-Bittan J, Bonnetain R, Amal A, Royer L, Rollet ME, Glasman P, Bergeot A, Nicolas M, Cadwallader JS, Boddaert J, Zerah L.   +11 more
europepmc   +1 more source

Complex social intervention for multidisciplinary teams to improve patient referrals in obstetrical care: protocol for a stepped wedge study design [PDF]

, 2016
Anita Romijn, Martine C. de Bruijne, Pim W. Teunissen, Christianne J.M. de Groot, Cordula Wagner   +4 more
openalex   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source