Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
Understanding the acute care context to inform palliative care improvements: a qualitative study of hospital-based multidisciplinary clinicians. [PDF]
Virdun C+4 more
europepmc +1 more source
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li+11 more
wiley +1 more source
The Power of Words: what if the health system lived up to its role in addressing frequent use of services? [PDF]
Hudon C, Rubenstein D.
europepmc +1 more source
Four-Year Educational and Patient Care Outcomes of a Team-Based Primary Care Longitudinal Clerkship
Bruce L. Henschen+6 more
openalex +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source
Translation, cultural adaptation, and psychometric properties of the MISSCARE survey OR - Swedish version. [PDF]
von Vogelsang AC+4 more
europepmc +1 more source
Can pharmacists collaborate with patients and interprofessional teams to reduce medication‐related risk at interfaces of care and improve meaningful patient outcomes? [PDF]
Olavo Fernandes, Michelle Baker
openalex +1 more source
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song+37 more
wiley +1 more source