Results 301 to 310 of about 19,050,112 (390)

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

guidance for rehabilitation patients with COVID-19 discharged from hospital integration of traditional Chinese and western medicine

, 2020
Jing Zhou
openalex   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Transitional Care Support for Patients with Heart Failure: A Qualitative Study of Nursing Practices by Ward, Discharge Planning, and Visiting Nurses. [PDF]

Kobe J Med Sci
Takahashi M, Taru C, Fukuda A, Miyawaki I.   +3 more
europepmc   +1 more source

EDUCATIONAL NEEDS OF CORONARY ARTERY BYPASS GRAFT PATIENTS AT TIME OF DISCHARGE

, 2002
Shafipoor, A Najaf Yarandi, Z Mohammad Aliha, Fahimeh Alsadat Hosseini   +3 more
openalex   +1 more source

Factors associated with postoperative discharge readiness and continuing care needs in patients with lung cancer undergoing fast-track surgery: A prospective cohort study

Na Zhang, Huan‐Huan Zhang, Yan Liu
openalex   +1 more source

A Multipronged Intervention to Improve Outpatient Care Following Hospitalization With Acute Kidney Injury: An Implementation Study Protocol. [PDF]

Can J Kidney Health Dis
Wong MMY, Birks P, Enilama O, Yu JSW, Singh A, Levin A.   +5 more
europepmc   +1 more source

'Take care of it, general practitioner' - a qualitative study about barriers and needs in general practice caring for people newly diagnosed with dementia. [PDF]

BMC Prim Care
Hegerath-Segler FM, Giehl C, Vollmar HC, Otte IC.   +3 more
europepmc   +1 more source