Results 101 to 110 of about 22,396,701 (403)

Co-production in HIV research: a case study from the COVID-19 pandemic

Research Involvement and Engagement
Background Co-produced research is an approach where people with lived experience voluntarily engage as collaborators throughout the entire research process.
Vasiliki Papageorgiou, Jane Bruton, Halle Johnson, Silvia Petretti, Wezi Thamm, Joshua Anderson, Husseina Hamza, Helen Ward   +7 more
doaj   +1 more source

When the patient is the expert: measuring patient experience and satisfaction with care

Bulletin of the World Health Organization, 2019
In 2018, three independent reports were published, emphasizing the need for attention to, and improvements in, quality of care to achieve effective universal health coverage.
E. Larson, Jigyasa Sharma, Meghan A. Bohren, Ö. Tunçalp   +3 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Impact of daily, oral pre-exposure prophylaxis on the risk of bacterial sexually transmitted infections among cisgender women: a systematic review and narrative synthesis [version 2; peer review: 2 approved]

Wellcome Open Research, 2022
Background: There are concerns that the use of pre-exposure prophylaxis (PrEP) may result in an increased incidence of sexually transmitted infections (STIs).
Helen Ward, Erica Crittendon, Vasiliki Papageorgiou, Bethan Davies, Flavien Coukan   +4 more
doaj  

Assessing the Patient Experience of Hypoparathyroidism Symptoms: Development of the Hypoparathyroidism Patient Experience Scale-Symptom (HPES-Symptom)

Patient, 2019
Hypoparathyroidism is a rare endocrine disorder characterized by absent or inappropriately low levels of circulating parathyroid hormone. Patients with hypoparathyroidism receiving standard-of-care therapy report debilitating physical and cognitive ...
M. Brod, L. Waldman, Alden Smith, D. Karpf   +3 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Design and Integration of a Texting Tool to Keep Patients’ Family Members Updated During Hospitalization: Family Members’ Perspectives

Journal of Patient Experience, 2023
While there is an evolving literature on the benefits of texting and patient-centered technologies, texting initiatives have not focused on family members. We sought to identify patients’ family members’ perspectives on facilitators and barriers to using
Courtenay R. Bruce JD, MA, Ashleigh Kamencik-Wright MBA, Natalie Zuniga-Georgy MS, Thomas M. Vinh RN, BSN, Hema Shah MSN, BSN, RN, BS, Jamie Shallcross BS, Charlie Giammattei BS, Colleen O’Rourke BS, Mariana Smith MHA, Lindsey Bruchhaus MSN, RN, Yashica Bowens BSN, MBA, MHCM, Kimberly Goode MA, Lee Ann Arabie BS, Katherine Sauceda BA, Majeedah Pacha MPH, Sandra Martinez MBA, James Chisum BA, R. Benjamin Saldaña DO FACEP, S. Nicholas Desai MD, Melina Awar MD, FACP, FHM, Thomas R. Vernon BSN, EdM   +20 more
doaj   +1 more source

Exploring the hospital patient journey: What does the patient experience?

PLoS ONE, 2019
Purpose To understand how different methodologies of qualitative research are able to capture patient experience of the hospital journey. Methods A qualitative study of orthopaedic patients admitted for hip and knee replacement surgery in a 250-bed ...
Raffaella Gualandi, C. Masella, Daniela Viglione, D. Tartaglini   +3 more
semanticscholar   +1 more source

Implications of customer participation in outsourcing noncore services to third parties [PDF]

, 2020
Purpose Focal service providers increasingly involve customers in the decision-making about outsourcing parts of the service delivery process to third parties.
De Pourcq, Kaat, Gemmel, Paul, Larivière, Bart, Trybou, Jeroen, Verleye, Katrien   +4 more
core   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source