This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
In clinical hand osteoarthritis research, self-reported pain questionnaires do not reflect the patient experience. [PDF]
van der Meulen C+5 more
europepmc +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
Patient experience with cancer care in low- and middle-income Asian countries: a cross-sectional study of patients with advanced cancer. [PDF]
Andres EB+16 more
europepmc +1 more source
Patient-Centered Healthcare: From Patient Experience to Human Experience
Muhammad Hasan Abid+3 more
openaire +3 more sources
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi+6 more
wiley +1 more source
Relationship between the volume and type of appointments in general practice and patient experience: an observational study in England. [PDF]
Burch P, Whittaker W, Lau YS.
europepmc +1 more source
Matrix Tropism Influences Endometriotic Cell Attachment Patterns
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault+7 more
wiley +1 more source
The Role of a Nurse in a Programme for Patients Undergoing Transcatheter Aortic Valve Implantation: Impact on Outcomes and Patient Experience. [PDF]
González-Cebrian M+9 more
europepmc +1 more source
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput+5 more
wiley +1 more source