Results 71 to 80 of about 22,396,701 (403)

A qualitative exploration of participant and investigator perspectives from the TRED‐HF trial

open access: yesESC Heart Failure, 2021
Aims We explored the experiences and motivations of participants and staff who took part in the TRED‐HF trial (Therapy withdrawal in REcovered Dilated cardiomyopathy). Methods and results We conducted a qualitative study, using semi‐structured interviews,
Vasiliki Papageorgiou   +8 more
doaj   +1 more source

Physicians' Experiences as Patients with Statin Side Effects: A Case Series. [PDF]

open access: yes, 2017
Physicians are among those prescribed statins and therefore, subject to potential statin adverse effects (AEs). There is little information on the impact of statin AEs on physicians affected by them. We sought to assess the character and impact of statin
Golomb, Beatrice Alexandra   +2 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Catarrh - the patient experience

open access: yesRhinology journal, 2011
Background: No study to date has looked at the symptoms of chronic catarrh as defined by the patients themselves. We looked to explore the catarrh experience through the eyes of patients using a qualitative approach. Methodology/principal: Forty-eight patients referred to Secondary Care with chronic catarrh, postnasal drip or persistent throat ...
Cathcart RA, Wilson JA
openaire   +4 more sources

Editorial: Patient voice and the patient experience

open access: yesRadiography, 2023
This is the author accepted manuscript.
Meertens, R, Hancock, A, Hyde, E
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Dying, death and bereavement: developing a national survey of bereaved relatives

open access: yesBMC Palliative Care, 2023
Background Assessing and measuring the experience and quality of care provided is central to the improvement of care delivery of all healthcare systems.
Diarmuid Ó Coimín   +4 more
doaj   +1 more source

Softer perspectives on enhancing the patient experience using IS/IT [PDF]

open access: yes, 2010
Purpose – This paper aims to argue that the implementation of the Choose and Book system has failed due to the inability of project sponsors to appreciate the complex and far-reaching softer implications of the implementation, especially in a complex ...
Grainger, Tracey   +4 more
core   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

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