Results 161 to 170 of about 83,612 (293)

Lennox–Gastaut syndrome unveiled: Advancing diagnosis, therapies, and advocacy‐insights from the Genoa International Workshop

open access: yesEpilepsia, EarlyView.
Abstract Lennox–Gastaut syndrome (LGS) is one of the most severe, yet one of the most discussed, childhood‐onset developmental and epileptic encephalopathies (DEEs). Dissent among epileptologists on the definition and minimum set of electroclinical features derives from the high etiological heterogeneity within the syndrome, which could make its ...
Antonella Riva   +40 more
wiley   +1 more source

OnabotulinumtoxinA treatment among diverse racial groups: Post hoc analysis of the phase 4 Chronic migraine OnabotulinuMtoxinA Prolonged Efficacy open‐Label (COMPEL) trial

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective Examine treatment responses to and safety of onabotulinumtoxinA for the preventive treatment of chronic migraine (CM) among diverse racial groups. Background Evidence suggests there are differences in headache treatment patterns, symptom profiles, and burden based on race.
Andrew M. Blumenfeld   +9 more
wiley   +1 more source

Latent Profiles of Nurses' Insomnia, Fatigue, Recovery, Psychological Distress and Burnout During the COVID‐19 Pandemic: Examining the Role of Organisational Support

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify latent profiles of insomnia, fatigue, recovery, psychological distress and burnout among hospital nurses; examine variations in personal and work‐related characteristics across profiles; investigate associations between profiles and outcomes such as patient care quality, nursing work satisfaction and workplace satisfaction ...
Hyeonmi Cho   +2 more
wiley   +1 more source

The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning   +3 more
wiley   +1 more source

Effects of Psychosocial Interventions on Loneliness Amongst Long‐Term Care Residents: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Background Loneliness significantly affects the physical and mental health of older adults, particularly those in long‐term care settings. Despite the high prevalence of loneliness, comprehensive reviews on psychosocial interventions targeting loneliness in these populations are scarce.
Jodie Cheuk‐Yan Szeto   +4 more
wiley   +1 more source

Family Bereavement Support Interventions in Specialist Adult Palliative Care: A Rapid Mixed‐Methods Systematic Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To synthesise evidence on the impact of pre‐ and post‐loss family support interventions on bereavement outcomes and families' perceptions of their usefulness and benefits in specialist palliative care. Design A rapid mixed‐methods systematic review drawing on JBI and Cochrane guidance.
Torsten Schwalbach   +3 more
wiley   +1 more source

Multilevel risk and protective factors for self‐harm, suicidal ideation and suicide attempt in adolescents

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Better characterising risk and protective factors for suicidal distress and self‐harm in adolescents may facilitate better targeting of interventions that address underlying vulnerabilities. However, few previous longitudinal studies have: (1) sufficient power to identify key risk and protective factors, (2) limited representativeness to the
Alison L. Calear   +7 more
wiley   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami   +6 more
wiley   +1 more source

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