Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Evidence of Validity of the Knowledge Assessment Instrument on Metabolic Syndrome [PDF]
Paidéia (Ribeirão Preto): This study aimed to develop and validate an instrument to analyze adults’ knowledge about metabolic syndrome. The instrument was developed via documentary research, resulting in 40 statements with Likert-type responses, organized into three domains: (1)
Jhainieiry Cordeiro Famelli Ferret +3 more
doaj +1 more source
Psychometric Properties of the Patient Health Questionnaire-9 in Elderly Chilean Primary Care Users
Frontiers in Psychiatry, 2020 Background: This study aimed to assess the measurement properties (reliability, factor structure, and criterion validity) of the Patient Health Questionnaire (PHQ-9) as an instrument for screening major depressive disorder (MDD) in elderly primary care ...
Joseph Aslan +7 more
doaj +1 more source
Attitudes of Japanese Medical Students towards Disclosure of a Diagnosis of Life-threatening Illness [PDF]
, 2009 In this study we investigated the attitudes of Japanese medical students toward being informed of a diagnosis of life-threatening illness. Fourth-year medical students from 20 randomly sampled universities were administered questionnaires that examined ...
Haseba, Yahiro +9 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Psychoeducational interventions in adolescent depression: A systematic review [PDF]
, 2017 Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions.
Bevan Jones, Rhys +6 more
core +3 more sources
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022 Background and Objectives: This study aims to predict the improvement in the symptoms of generalized anxiety disorder (GAD) based on distress tolerance, tolerance of uncertainty, and cognitive avoidance. Methods: This is a descriptive correlational study.
Roza Abdellahzadeh, Mohsen Maroufi
doaj
The TOSCA Registry for Tuberous Sclerosis-Lessons Learnt for Future Registry Development in Rare and Complex Diseases. [PDF]
, 2019 Introduction: The TuberOus SClerosis registry to increase disease Awareness (TOSCA) is an international disease registry designed to provide insights into the clinical characteristics of patients with Tuberous Sclerosis Complex (TSC).
Beaure d'Augères, Guillaume +29 more
core +2 more sources
The diagnostic accuracy of the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-8 (PHQ-8), and Patient Health Questionnaire-9 (PHQ-9) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses [PDF]
Systematic Reviews, 2014 Major depressive disorder (MDD) may be present in 10%-20% of patients in medical settings. Routine depression screening is sometimes recommended to improve depression management. However, studies of the diagnostic accuracy of depression screening tools have typically used data-driven, exploratory methods to select optimal cutoffs.
Thombs, Brett D. +12 more
openaire +2 more sources