Results 81 to 90 of about 1,447 (221)

Effect of Personal Protective Equipment on the Prevention of SARS-CoV-2 Infection in Healthcare Workers. [PDF]

J Korean Med Sci
Lee SJ, Kim E, Im JH, Lee JS, Baek J.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Anorexia nervosa symptoms are induced after specific gut microbiota dysbiosis transfer in germ-free mice. [PDF]

Gut Microbes
Gabriel-Segard T, Heberden C, Mondot S, Duquesnoy M, Dicembre M, Naudon L, Philippe C, Maximin E, Blais A, Jacota M, Lapaque N, Blottière HM, Paul S, Doré J, Rabot S, Hanachi M.   +15 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Operator stress factors and cell contamination risks in cell processing facilities: An online survey-based analysis. [PDF]

Regen Ther
Sugahara Y, Mizuno M, Miyashita N, Katano H, Sekiya I.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

A novel clinical data acquisition device: Towards real time cardiovascular modelling in the ICU. [PDF]

HardwareX
Cushway J, Chase JG, Desaive T, Murphy L, Flett IL, Shaw GM.   +5 more
europepmc   +1 more source

Successful In Situ Targeting of Pancreatic Tumors in a Novel Orthotopic Porcine Model Using Histotripsy. [PDF]

Ultrasound Med Biol, 2023
Imran KM, Gannon J, Morrison HA, Tupik JD, Tintera B, Nagai-Singer MA, Ivester H, Madanick JM, Hendricks-Wenger A, Uh K, Luyimbazi DT, Edwards M, Coutermarsh-Ott S, Eden K, Byron C, Clark-Deener S, Lee K, Vlaisavljevich E, Allen IC.   +18 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Strengthening hospital resilience to earthquakes: a public health review of seismic risk reduction programs in the Middle East. [PDF]

Int J Emerg Med
Almukhlifi Y, Alsulami M, Alharbi A, Howsawi T, Hussain A, Alfageeh R, Alzahrani A, Alshareef E, Salah A, Radey R, Sultan M.   +10 more
europepmc   +1 more source