Results 31 to 40 of about 479,454 (261)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

One Jefferson News October 2017 [PDF]

open access: yes, 2017
Over the past month, we have continued our One Jefferson journey and achieved a number of integration successes for the organization as well as our patient and student communities.
Performance Excellence,
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The CDH patient perspective journey

open access: yesFrontiers in Pediatrics, 2023
BackgroundCongenital Diaphragmatic Hernia is a malformation of the diaphragm resulting in ongoing clinical symptoms and problems. Mortality remains high, particularly where there are other issues involved. Tracking a patient throughout their lifetime to understand the full impact on health and function is challenging.
openaire   +3 more sources

The Triple Aim Journey: Improving Population Health and Patients' Experience of Care, While Reducing Costs [PDF]

open access: yes, 2010
Provides an overview of the Institute for Healthcare Improvement's initiative designed to help improve population health, enhance patients' experience of care, and slow the growth of per capita costs.
Douglas McCarthy, Sarah Klein
core  

Implementing digital resources for clinicians' and patients' varying needs. [PDF]

open access: yes, 2005
This paper presents an overview of several evidence-based medicine and patient information studies conducted across the UK health service over a 4 year period, investigating clinicians', managers', and patients' perceptions of digital resources ...
Anne Adams   +31 more
core   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Which interval is most crucial to presentation and survival in gastroesophageal cancer: a systematic review [PDF]

open access: yes, 2017
Aim: The aim of this study was to identify the most crucial interval to encourage earlier diagnosis in with gastroesophageal cancer and to identify potential factors effecting this interval.
Khulusi, Sam, Lee, Amanda, Watson, Roger
core   +2 more sources

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Vital Sensory Kit For Use With Telemedicine In Developing Countries [PDF]

open access: yes, 2017
In many developing countries, a large percentage of the population lacks access to adequate healthcare. This is especially true in India where close to 70% of the population lives in rural areas and has little to no access to hospitals or clinics. People
Arrizon, Natalie   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy