Results 111 to 120 of about 22,517,059 (343)

Improving Detection of Rapid Cystic Fibrosis Disease Progression–Early Translation of a Predictive Algorithm Into a Point-of-Care Tool

IEEE Journal of Translational Engineering in Health and Medicine, 2019
The clinical course of cystic fibrosis (CF) lung disease is marked by acute drops of lung function, defined clinically as rapid decline. As such, lung function is monitored routinely through pulmonary function testing, producing hundreds of measurements ...
Rhonda D. Szczesniak, Cole Brokamp, Weiji Su, Gary L. Mcphail, John Pestian, John P. Clancy   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Detection and localisation of hesitant steps in people with Alzheimer's disease navigating routes of varying complexity

Healthcare Technology Letters, 2019
People with Alzheimer's disease (AD) have characteristic problems navigating everyday environments. While patients may exhibit abnormal gait parameters, adaptive gait irregularities when navigating environments are little explored or understood.
Ian McCarthy, Tatsuto Suzuki, Catherine Holloway, Teresa Poole, Chris Frost, Amelia Carton, Nick Tyler, Sebastian Crutch, Keir Yong   +8 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Review of sensors for remote patient monitoring [PDF]

, 2008
Remote patient monitoring (RPM) of physiological measurements can provide an efficient method and high quality care to patients. The physiological signals measurement is the initial and the most important factor in RPM.
Liu, Yuanlong, Sahandi, Reza
core  

Kablosuz Vücut Alan Ağları İle Mobil Sağlık İzleme Uygulaması

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2016
Her geçen gün hasta sayısındaki artış, hastane cihazlarının ve masraflarının pahalı olması, cihazların taşınabilir olmaması, doktor hasta arasında iletişim yetersizliği ve yatak sayılarının yetersiz kalması nedeniyle birçok önemli hastalığa zamanında ...
Köksal Gündoğdu, Ebru Gündoğdu, Ali Çalhan   +2 more
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Parkinson's Disease Remote Patient Monitoring During the COVID-19 Lockdown

Frontiers in Neurology, 2020
Objective: To evaluate the feasibility of a smartphone remote patient monitoring approach in a real-life Parkinson's disease (PD) cohort during the Italian COVID-19 lockdown.
F. Motolese, A. Magliozzi, Fiorella Puttini, Mariagrazia Rossi, F. Capone, Keren Karlinski, A. Stark‐Inbar, Ziv Yekutieli, V. Di Lazzaro, M. Marano   +9 more
semanticscholar   +1 more source

Collaborative Paradigm of Preventive, Personalized, and Precision Medicine With Point-of-Care Technologies

IEEE Journal of Translational Engineering in Health and Medicine, 2016
Recent advances in biosensors, medical instrumentation, and information processing and communication technologies (ICT) have enabled significant improvements in healthcare.
Atam P. Dhawan
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source