Results 41 to 50 of about 2,134,942 (300)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Sensorized Tip for Monitoring People with Multiple Sclerosis that Require Assistive Devices for Walking

Sensors, 2020
Multiple Sclerosis (MS) is a neurological degenerative disease with high impact on our society. In order to mitigate its effects, proper rehabilitation therapy is mandatory, in which individualisation is a key factor.
Asier Brull, Asier Zubizarreta, Itziar Cabanes, Ana Rodriguez-Larrad   +3 more
doaj   +1 more source

An evaluation of antimicrobial stewardship in community pharmacy [PDF]

, 2015
This study investigated several aspects of antimicrobial stewardship by gathering information from community pharmacists and members of the public. The aim was to identify how community pharmacists implement antimicrobial stewardship guidelines and ...
Hancock, Laura Jade, Mellor, Callan
core   +1 more source

Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study

Frontiers in Hematology
BackgroundDisease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.MethodsThis cross-sectional study used the validated Hematological Malignancy
Sam Salek, Samantha Nier, Zack Pemberton-Whiteley, Tatyana Ionova, Giuseppe Ianni, Giovanni Tripepi, Nick York, Nicole Schroeter, Kathryn Huntley, Michael Rynne, Denis Costello, Lidija Pecova, Esther Natalie Oliva   +12 more
doaj   +1 more source

Standard compliant communication of motion data in a telemonitoring system

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2015
Interoperability is regarded as one of the key factors for the high acceptance of a telemonitoring system. In a general telemonitoring scenario for motion tracking, data recorded by inertial sensors should be sent from the patient's home to a central ...
Piro, Neltje Emma, Baumann, Lisa, Kesztyüs, Tibor, Blechschmidt-Trapp, Ronald Archibald   +3 more
doaj   +1 more source

A smartphone-based Teleradiology system [PDF]

, 2014
The development of a teleradiology application for remote monitoring and processing of patient image data using 2nd generation mobile devices with enhanced network services, is of extreme interest, especially when the final means of display is a ...
Banitsas, K, Cavouras, D, Dimitropoulos, N, Georgiadis, P, Georgiou, H, Sidiropoulos, K, Tachakra, S   +6 more
core  

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

A deep learning model for estimating sedation levels using heart rate variability and vital signs: a retrospective cross-sectional study at a center in South Korea [PDF]

Acute and Critical Care
Background Optimal sedation assessment in critically ill children remains challenging due to the subjective nature of behavioral scales and intermittent evaluation schedules.
You Sun Kim, Bongjin Lee, Wonjin Jang, Yonghyuk Jeon, June Dong Park   +4 more
doaj   +1 more source

A study on preterm birth predictions using physiological signals, medical health record information and low‐dimensional embedding methods

IET Cyber-systems and Robotics, 2021
Preterm births have been seen to have psychological and financial implications; current surveys suggest that amongst the various methods of preterm prediction, there is yet to exist a reliable and standard means of predicting preterm births.
Ejay Nsugbe, Oluwarotimi William Samuel, Ibrahim Sanusi, Mojisola Grace Asogbon, Guanglin Li   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source